Evidence map›Paper›PMID 24018591›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2014

Laparoscopic Heller myotomy can be used as primary therapy for esophageal achalasia regardless of age.

Renato Salvador, Mario Costantini, Francesco Cavallin, Lisa Zanatta, Elena Finotti, Cristina Longo, Loredana Nicoletti, Giovanni Capovilla, Romeo Bardini, Giovanni Zaninotto

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Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Achalasia in Geriatric Patients: A Comprehensive Overview.Digestive diseases and sciences · 2026
    Review
  3. Re-operation after prior esophagomyotomy.Journal of visualized surgery · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Laparoscopic repair of late perforation following Heller myotomy due to overeating.Annals of the Royal College of Surgeons of England · 2020
    Article
  9. 2019 Seoul Consensus on Esophageal Achalasia Guidelines.Journal of neurogastroenterology and motility · 2020
    Review
  10. A Thousand and One Laparoscopic Heller Myotomies for Esophageal Achalasia: a 25-Year Experience at a Single Tertiary Center.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Article
  11. Dysphagia in the Elderly.Current treatment options in gastroenterology · 2017
    Review
  12. Observational
  13. Postoperative Gastroesophageal Reflux After Laparoscopic Heller-Dor for Achalasia: True Incidence with an Objective Evaluation.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017
    Article
  14. Mucosal Perforation During Laparoscopic Heller Myotomy Has No Influence on Final Treatment Outcome.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016
    Article
  15. Article
  16. The Impact of Heller Myotomy on Integrated Relaxation Pressure in Esophageal Achalasia.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016
    Article
  17. Review
  18. Therapeutic options in oesophageal dysphagia.Nature reviews. Gastroenterology & hepatology · 2015
    Review
  19. Controversies in management of achalasia.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2014
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Renato SalvadorDepartment of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Mario Costantini
Francesco Cavallin
Lisa Zanatta
Elena Finotti
Cristina Longo
Loredana Nicoletti
Giovanni Capovilla
Romeo Bardini
Giovanni Zaninotto
University of Padua · ITIstituto Oncologico Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLaparoscopic Heller-Dor surgery is the current treatment of choice for patients with esophageal achalasia, but elderly patients are generally referred for less invasive treatments (pneumatic dilations or botulinum toxin injections).

aimTo assess the effect of age on the surgical outcome of patients receiving laparoscopic Heller-Dor as primary treatment.

methodsDemographic and clinical findings were prospectively collected on patients undergoing laparoscopic Heller-Dor from 1992 to 2012. Patients were classified in three age brackets: group A (≤45 years), group B (45-70), and group C (≥70). Treatment was defined as a failure if the postoperative symptom score was >10th percentile of the preoperative score (i.e., >8). We consecutively performed the Heller-Dor in 571 achalasia patients, 305 (53.4 %) in group A, 226 (39.6 %) in group B, and 40 (7 %) in group C.

resultsThe mortality was nil; the conversion and morbidity rates were both 1.1 %. Group C patients had higher preoperative symptom scores (p = 0.02), while the symptom duration was similar in all three groups. Mucosal tears occurred in 17 patients (3 %): 6 (2 %) in group A, 8 (3.5 %) in group B, and 3 (7.5 %) in group C (p = 0.09). The postoperative hospital stay was slightly longer for group C (p = 0.06). DISCUSSION: The treatment failure rate was quite similar: 31 failures in group A (10.1 %), 19 in group B (8.4 %), and 3 in group C (7.5 %; p = 0.80). These failures were seen more in manometric pattern III (22.2 %, p = 0.002). Laparoscopic Heller-Dor can be used as the first therapeutic approach to achalasia even in elderly patients with an acceptable surgical risk.

Indexed as

AdultAgedAge FactorsEsophageal AchalasiaEsophageal Sphincter, LowerFemaleHumansLacerationsLaparoscopyLength of StayMaleManometryMiddle AgedMucous MembraneRetrospective StudiesSeverity of Illness Index

Identifiers

PMID24018591
OpenAlexW2046490246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.