ArticleExperimental neurology2013
Functional signature of recovering cortex: dissociation of local field potentials and spiking activity in somatosensory cortices of spinal cord injured monkeys.
Article in Experimental neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Transcranial focused ultrasound modulates spiking, LFP, and BOLD activity in the primate thalamus.Nature communications · 2026Article
- Multimodal Correspondence between Optogenetic fMRI, Electrophysiology, and Anatomical Maps of the Secondary Somatosensory Cortex in Nonhuman Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Differential Recovery of Submodality Touch Neurons and Interareal Communication in Sensory Input-Deprived Area 3b and S2 Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Dexmedetomidine - Commonly Used in Functional Imaging Studies - Increases Susceptibility to Seizures in Rats But Not in Wild Type Mice.Frontiers in neuroscience · 2020Article
- Reorganization of Higher-Order Somatosensory Cortex After Sensory Loss from Hand in Squirrel Monkeys.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Intrinsic functional architecture of the non-human primate spinal cord derived from fMRI and electrophysiology.Nature communications · 2019Article
- Cortical Representation of Pain and Touch: Evidence from Combined Functional Neuroimaging and Electrophysiology in Non-human Primates.Neuroscience bulletin · 2018Review
- Correlated Disruption of Resting-State fMRI, LFP, and Spike Connectivity between Area 3b and S2 following Spinal Cord Injury in Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Spinal cord neuron inputs to the cuneate nucleus that partially survive dorsal column lesions: A pathway that could contribute to recovery after spinal cord injury.The Journal of comparative neurology · 2015Article
- Parallel functional reorganizations of somatosensory areas 3b and 1, and S2 following spinal cord injury in squirrel monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Cortical neuron response properties are related to lesion extent and behavioral recovery after sensory loss from spinal cord injury in monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- The reactivation of somatosensory cortex and behavioral recovery after sensory loss in mature primates.Frontiers in systems neuroscience · 2014Review
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Authors and funding
5 authors.
Funding
Abstract
After disruption of dorsal column afferents at high cervical spinal levels in adult monkeys, somatosensory cortical neurons recover responsiveness to tactile stimulation of the hand; this reactivation correlates with a recovery of hand use. However, it is not known if all neuronal response properties recover, and whether different cortical areas recover in a similar manner. To address this, we recorded neuronal activity in cortical area 3b and S2 in adult squirrel monkeys weeks after unilateral lesion of the dorsal columns. We found that in response to vibrotactile stimulation, local field potentials remained robust at all frequency ranges. However, neuronal spiking activity failed to follow at high frequencies (≥15 Hz). We suggest that the failure to generate spiking activity at high stimulus frequency reflects a changed balance of inhibition and excitation in both area 3b and S2, and that this mismatch in spiking and local field potential is a signature of an early phase of recovering cortex (<two months).
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