ArticleACS nano2013
Fluorescent imaging of single nanoparticles and viruses on a smart phone.
Article in ACS nano, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
121 citing papers in PubMed.
- A smartphone-based particle diffusometry platform for sub-attomolar detection of Vibrio cholerae in environmental water.Biosensors & bioelectronics · 2020Trial
- Expanding High-Fidelity Multiplexing in Ultrasensitive Single-Molecule Protein Detection via Proximity Barcoding.Angewandte Chemie (International ed. in English) · 2026Article
- Paper-Based Analytical Devices Coupled with Fluorescence Detection and Smartphone Imaging: Advances and Applications.Sensors (Basel, Switzerland) · 2026Review
- Behavioral techniques for controlling visual stimuli to modulate visual processing in the brain and their implementation in augmented reality technology.Frontiers in neuroscience · 2026Review
- A framework for real-time image detection of bioaerosols.Scientific reports · 2025Article
- Enhancing Biomarker Detection and Imaging Performance of Smartphone Fluorescence Microscopy Devices.Biosensors · 2025Article
- Advances in Portable Optical Microscopy Using Cloud Technologies and Artificial Intelligence for Medical Applications.Sensors (Basel, Switzerland) · 2024Review
- Deep learning-assisted smartphone-based quantitative microscopy for label-free peripheral blood smear analysis.Biomedical optics express · 2024Article
- Quantitative, high-sensitivity measurement of liquid analytes using a smartphone compass.Nature communications · 2024Article
- A digital image colorimetry system based on smart devices for immediate and simultaneous determination of enzyme-linked immunosorbent assays.Scientific reports · 2024Article
- Dual-wavelength metalens enables Epi-fluorescence detection from single molecules.Nature communications · 2024Article
- Dual imaging technique for a real-time inspection system of foreign object detection in fresh-cut vegetables.Current research in food science · 2024Article
- Portable sensing devices for smart healthcare and prevention of lead poisoning.Journal of the Chinese Medical Association : JCMA · 2023Review
- Wave optics of imaging with contact ball lenses.Scientific reports · 2023Article
- A Low-Cost Modular Imaging System for Rapid, Multiplexed Immunofluorescence Detection in Clinical Tissues.International journal of molecular sciences · 2023Review
- Single-Molecule Optical Biosensing: Recent Advances and Future Challenges.ACS physical chemistry Au · 2023Review
- Fully Integrated Ultra-thin Intraoperative Micro-imager for Cancer Detection Using Upconverting Nanoparticles.Molecular imaging and biology · 2023Article
- Article
- Review
- Improved immunoassay sensitivity and specificity using single-molecule colocalization.Nature communications · 2022Article
61 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors.
Funding
Abstract
Optical imaging of nanoscale objects, whether it is based on scattering or fluorescence, is a challenging task due to reduced detection signal-to-noise ratio and contrast at subwavelength dimensions. Here, we report a field-portable fluorescence microscopy platform installed on a smart phone for imaging of individual nanoparticles as well as viruses using a lightweight and compact opto-mechanical attachment to the existing camera module of the cell phone. This hand-held fluorescent imaging device utilizes (i) a compact 450 nm laser diode that creates oblique excitation on the sample plane with an incidence angle of ~75°, (ii) a long-pass thin-film interference filter to reject the scattered excitation light, (iii) an external lens creating 2× optical magnification, and (iv) a translation stage for focus adjustment. We tested the imaging performance of this smart-phone-enabled microscopy platform by detecting isolated 100 nm fluorescent particles as well as individual human cytomegaloviruses that are fluorescently labeled. The size of each detected nano-object on the cell phone platform was validated using scanning electron microscopy images of the same samples. This field-portable fluorescence microscopy attachment to the cell phone, weighing only ~186 g, could be used for specific and sensitive imaging of subwavelength objects including various bacteria and viruses and, therefore, could provide a valuable platform for the practice of nanotechnology in field settings and for conducting viral load measurements and other biomedical tests even in remote and resource-limited environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.