ArticlePloS one2013
Signatures of rapid evolution in urban and rural transcriptomes of white-footed mice (Peromyscus leucopus) in the New York metropolitan area.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 86 citations in OpenAlex.
- The Transcriptomic Response Along an Urbanization Gradient Is Also Temperature-Dependent in a Freshwater Insect.Molecular ecology · 2026Article
- Increased abundance of Limosilactobacillus reuteri in the gut of selectively bred high-tameness mice and its association with behavioural changes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- A systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2026Review
- Urbanisation Drives Microevolution in the Egyptian Fruit Bat (Evolutionary applications · 2026Article
- The One Health approach in urban ecosystem rehabilitation: An evidence-based framework for designing sustainable cities.iScience · 2024Review
- Limited evidence for genetic differentiation or adaptation in two amphibian species across replicated rural-urban gradients.Evolutionary applications · 2024Article
- Urbanization drives adaptive evolution in a Neotropical bird.Current zoology · 2023Article
- Ingrained city rhythms: flexible activity timing but more persistent circadian pace in urban birds.Proceedings. Biological sciences · 2023Article
- Genome-wide parallelism underlies contemporary adaptation in urban lizards.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- An environmental gradient dominates ecological and genetic differentiation of marine invertebrates between the North and Baltic Sea.Ecology and evolution · 2022Article
- Hibernation Conditions Contribute to the Differential Resistance to Cadmium between Urban and Forest Ant Colonies.Animals : an open access journal from MDPI · 2021Article
- Urbanization is associated with modifications in DNA methylation in a small passerine bird.Evolutionary applications · 2021Article
- Growing in the city: Urban evolutionary ecology of avian growth rates.Evolutionary applications · 2021Article
- Dispersal ability predicts spatial genetic structure in native mammals persisting across an urbanization gradient.Evolutionary applications · 2021Article
- A roadmap for urban evolutionary ecology.Evolutionary applications · 2019Article
- Phenotypic selection on floral traits in an urban landscape.Proceedings. Biological sciences · 2018Article
- Contrasting the effects of natural selection, genetic drift and gene flow on urban evolution in white clover (Proceedings. Biological sciences · 2018Article
- Great tits and the city: Distribution of genomic diversity and gene-environment associations along an urbanization gradient.Evolutionary applications · 2018Article
- An updated genetic map of Peromyscus with chromosomal assignment of linkage groups.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Article
- Divergent habitat use of two urban lizard species.Ecology and evolution · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Urbanization is a major cause of ecological degradation around the world, and human settlement in large cities is accelerating. New York City (NYC) is one of the oldest and most urbanized cities in North America, but still maintains 20% vegetation cover and substantial populations of some native wildlife. The white-footed mouse, Peromyscusleucopus, is a common resident of NYC's forest fragments and an emerging model system for examining the evolutionary consequences of urbanization. In this study, we developed transcriptomic resources for urban P. leucopus to examine evolutionary changes in protein-coding regions for an exemplar "urban adapter." We used Roche 454 GS FLX+ high throughput sequencing to derive transcriptomes from multiple tissues from individuals across both urban and rural populations. From these data, we identified 31,015 SNPs and several candidate genes potentially experiencing positive selection in urban populations of P. leucopus. These candidate genes are involved in xenobiotic metabolism, innate immune response, demethylation activity, and other important biological phenomena in novel urban environments. This study is one of the first to report candidate genes exhibiting signatures of directional selection in divergent urban ecosystems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.