Evidence map›Paper›PMID 24014503›Full record

Trial reportNeurology2013

Randomized trial of cognitive speed of processing training in Parkinson disease.

Jerri D Edwards, Robert A Hauser, Melissa L O'Connor, Elise G Valdés, Theresa A Zesiewicz, Ergun Y Uc

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of cognitive rehabilitation in Parkinson disease: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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  6. Cognitive training for people with mild to moderate dementia.The Cochrane database of systematic reviews · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jerri D EdwardsFrom the School of Aging Studies (J.D.E., E.G.V.) and Department of Neurology (R.A.H., T.A.Z.), University of South Florida, Tampa; Department of Human Development and Family Science (M.L.O.), North Dakota State University, Fargo; Department of Neurology (E.Y.U.), University of Iowa, Iowa City; and Neurology Service (E.Y.U.), Veterans Affairs Medical Center, Iowa City.
Robert A Hauser
Melissa L O'Connor
Elise G Valdés
Theresa A Zesiewicz
Ergun Y Uc

Funding

Cognitive Speed of Processing Training Among Persons with Parkinson?s DiseaseR21AG033332 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI EDWARDS, JERRI · 2009 to 2010
$319k
NIA NIH HHS 1R21AG033332NIA NIH HHS R21 AG033332
6 · The paper itself

Abstract

objectiveTo examine the efficacy of cognitive speed of processing training (SOPT) among individuals with Parkinson disease (PD). Moderators of SOPT were also examined.

methodsEighty-seven adults, 40 years of age or older, with a diagnosis of idiopathic PD in Hoehn & Yahr stages 1-3 and on a stable medication regimen were randomized to either 20 hours of self-administered SOPT (using InSight software) or a no-contact control condition. Participants were assessed at baseline and after 3 months of training (or an equivalent delay). The primary outcome measure was useful field of view test (UFOV) performance, and secondary outcomes included cognitive self-perceptions and depressive symptoms.

resultsResults indicated that participants randomized to SOPT experienced significantly greater improvements on UFOV performance relative to controls, Wilks λ = 0.938, F 1,72 = 4.79, p = 0.032, partial η(2) = 0.062. Findings indicated no significant effect of training on secondary outcomes, Wilks λ = 0.987, F2,70 < 1, p = 0.637, partial η(2) = 0.013.

conclusionsPatients with mild to moderate stage PD can self-administer SOPT and improve their cognitive speed of processing, as indexed by UFOV (a robust predictor of driving performance in aging and PD). Further research should establish if persons with PD experience longitudinal benefits of such training and if improvements translate to benefits in functional activities such as driving. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that SOPT improves UFOV performance among persons in the mild to moderate stages of PD.

Indexed as

AdultAgedAged, 80 and overAnalysis of VarianceCognition DisordersCognitive Behavioral TherapyFemaleHumansMaleMental Status ScheduleMiddle AgedNeuropsychological TestsParkinson DiseasePsychomotor PerformanceSelf Concept

Identifiers

PMID24014503
PMCPMC3806923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.