ReviewWiley interdisciplinary reviews. Developmental biology2013
Retinal differentiation in Drosophila.
Review in Wiley interdisciplinary reviews. Developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
89 citing papers in PubMed, 151 citations in OpenAlex.
- Small Scale Dissection and Antibody Staining of Eye-Antennal and Wing Imaginal Discs from Drosophila melanogaster.Journal of visualized experiments : JoVE · 2026Article
- Glia Regulate the Timing of Photoreceptor Differentiation in the Drosophila Visual System.Glia · 2026Article
- Expanding the fly eye gene regulatory network: From Drosophila to the hoverfly Episyrphus balteatus.PLoS genetics · 2026Article
- Generation and maintenance of apical rib-like actin fibers in epithelial support cells of the Drosophila eye.Development (Cambridge, England) · 2026Article
- Retinal calcium waves coordinate uniform tissue patterning of theScience (New York, N.Y.) · 2025Article
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- NF-κB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model.PLoS biology · 2025Article
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- Extramacrochaetae regulates Notch signaling in thebioRxiv : the preprint server for biology · 2024Article
- Single-cell sequencing suggests a conserved function of Hedgehog-signalling in spider eye development.EvoDevo · 2024Article
- The Id protein Extramacrochaetae restrains the E protein Daughterless to regulate Notch, Rap1, and Sevenless within the R7 equivalence group of the Drosophila eye.Biology open · 2024Article
- Genome-Wide Association Study and transcriptome analysis reveals a complex gene network that regulates opsin gene expression and cell fate determination inbioRxiv : the preprint server for biology · 2024Article
- A single cell RNA sequence atlas of the early Drosophila larval eye.BMC genomics · 2024Article
- Eye proteome of Drosophila melanogaster.Proteomics · 2024Article
- Loss of the endoplasmic reticulum protein Tmem208 affects cell polarity, development, and viability.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- RNA-binding protein Nocte regulates Drosophila development by promoting translation reinitiation on mRNAs with long upstream open reading frames.Nucleic acids research · 2024Article
- Dachshund and C-terminal Binding Protein bind directly duringmicroPublication biology · 2024Article
- A novel proneural function of Asense is integrated with the sequential actions of Delta-Notch, L'sc and Su(H) to promote the neuroepithelial to neuroblast transition.PLoS genetics · 2023Article
- Peripodial adherens junctions regulate Ajuba-Yorkie signaling to preserve fly eye morphology.Biology open · 2023Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Drosophila eye development has been extensively studied, due to the ease of genetic screens for mutations disrupting this process. The eye imaginal disc is specified during embryonic and larval development by the Pax6 homolog Eyeless and a network of downstream transcription factors. Expression of these factors is regulated by signaling molecules and also indirectly by growth of the eye disc. Differentiation of photoreceptor clusters initiates in the third larval instar at the posterior of the eye disc and progresses anteriorly, driven by the secreted protein Hedgehog. Within each cluster, the combined activities of Hedgehog signaling and Notch-mediated lateral inhibition induce and refine the expression of the transcription factor Atonal, which specifies the founding R8 photoreceptor of each ommatidium. Seven additional photoreceptors, followed by cone and pigment cells, are successively recruited by the signaling molecules Spitz, Delta, and Bride of sevenless. Combinations of these signals and of intrinsic transcription factors give each ommatidial cell its specific identity. During the pupal stages, rhodopsins are expressed, and the photoreceptors and accessory cells take on their final positions and morphologies to form the adult retina. Over the past few decades, the genetic analysis of this small number of cell types arranged in a repetitive structure has allowed a remarkably detailed understanding of the basic mechanisms controlling cell differentiation and morphological rearrangement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.