ArticleIndian journal of pediatrics2014
Precocious puberty--perspectives on diagnosis and management.
Article in Indian journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Preventive Effect ofPlants (Basel, Switzerland) · 2021Article
- Gonadotropin-releasing hormone stimulation test and diagnostic cutoff in precocious puberty: a mini review.Annals of pediatric endocrinology & metabolism · 2020Article
- Influence of Gonadotropin Hormone Releasing Hormone Agonists on Interhemispheric Functional Connectivity in Girls With Idiopathic Central Precocious Puberty.Frontiers in neurology · 2020Article
- Serum Kisspeptin and AMH Levels Are Good References for Precocious Puberty Progression.International journal of endocrinology · 2020Article
- Acupuncture Improving Early Sexual Development of Girls with Peripheral Precocious Puberty: A Prospective Cohort Study.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Is a Combination of a GnRH Agonist and Recombinant Growth Hormone an Effective Treatment to Increase the Final Adult Height of Girls with Precocious or Early Puberty?International journal of endocrinology · 2018Article
- The Effect of Bisphenol A on Puberty: A Critical Review of the Medical Literature.International journal of environmental research and public health · 2017Review
- Precocious puberty: An experience from a major teaching hospital in Central Saudi Arabia.Sudanese journal of paediatrics · 2017Article
- A Gonadotropin-Releasing Hormone (GnRH) Stimulation Test Before and After GnRH Analogue Treatment for Central Precocious Puberty: Has the GnRH Test been Adequately Simplified?Indian journal of pediatrics · 2015Article
- Precocious Puberty, GnRH Stimulation Test and Monitoring GnRH Analog Therapy.Indian journal of pediatrics · 2015Article
- A systematic review on the effects of environmental exposure to some organohalogens and phthalates on early puberty.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Review
- Serum bisphenol A concentration and premature thelarche in female infants aged 4-month to 2-year.Indian journal of pediatrics · 2015Article
- Postinjection Muscle Fibrosis from Lupron.Case reports in pediatrics · 2015Article
- Current issues in pediatric endocrinology.Indian journal of pediatrics · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term 'precocious puberty' signifies the onset of secondary sexual characters before the age of 9 y in boys and 8 y in girls. Menarche before 9.5 y is also considered precocious. These definitions are constantly evolving due to the secular trends observed all over the world. It is crucial to decide whether the child has central (gonadotropin-dependent, GDPP) or peripheral (gonadotropin-independent, GIPP) form of precocious puberty. Some benign conditions such as premature thelarche and premature pubarche may mimic precocious puberty. A systematic approach with detailed history and clinical examination helps to arrive at a diagnosis in most cases. An underlying neurologic disorder is more likely in a very young boy. Basal LH level is the best screening test to diagnose GDPP. LH level less than 0.1 IU/L by a very sensitive assay indicates prepubertal stage. Stimulation tests using gonadotropin releasing hormone (GnRH) or its analog (GnRHa), leuprolide help to confirm the diagnosis of GDPP. High resolution MRI of brain helps to detect abnormalities in hypothalamus and pituitary region. GnRH analogs (GnRHa) are the only effective treatment for GDPP at present. In girls, breast size may regress; menses ceases and vaginal mucosa becomes non-estrogenized. In boys testicular volumes remain static or decrease and genital growth regresses. The effects of GnRH analogs are reversible on discontinuation of therapy, with restoration of normal function within 3 mo after stopping treatment. Treatment of GIPP however is far from satisfactory.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.