ArticleGenes & development2013
Physical clustering of FLC alleles during Polycomb-mediated epigenetic silencing in vernalization.
Article in Genes & development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Molecular integration of seasonal temperature signals in flowering time control.Nature reviews. Genetics · 2026Review
- VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing.Molecular cell · 2025Article
- SlimVar for rapid in vivo single-molecule tracking of chromatin regulators in plants.Nature communications · 2025Article
- Modular in vivo assembly of Arabidopsis FCA oligomers into condensates competent for RNA 3' processing.The EMBO journal · 2025Article
- Role ofInternational journal of molecular sciences · 2025Article
- Integrating Dynamic 3D Chromatin Architecture and Gene Expression Alterations Reveal Heterosis inInternational journal of molecular sciences · 2024Article
- Location, location, location: Nuclear pore complexes tether flowering loci to nuclear envelope to boost gene expression.The Plant cell · 2024Article
- The nuclear pore Y-complex functions as a platform for transcriptional regulation of FLOWERING LOCUS C in Arabidopsis.The Plant cell · 2024Article
- Plant 3D Chromatin Organization: Important Insights from Chromosome Conformation Capture Analyses of the Last 10 Years.Plant & cell physiology · 2021Review
- Modeling the 3D genome of plants.Nucleus (Austin, Tex.) · 2021Article
- Perspective: 50 years of plant chromosome biology.Plant physiology · 2021Article
- ANCHOR: A Technical Approach to Monitor Single-Copy Locus LocalizationFrontiers in plant science · 2021Article
- Tidying-up the plant nuclear space: domains, functions, and dynamics.Journal of experimental botany · 2020Review
- Transcriptome and epigenome analyses of vernalization in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2020Article
- Probing the 3D architecture of the plant nucleus with microscopy approaches: challenges and solutions.Nucleus (Austin, Tex.) · 2019Review
- Light and temperature shape nuclear architecture and gene expression.Current opinion in plant biology · 2018Review
- Altered chromatin compaction and histone methylation drive non-additive gene expression in an interspecific Arabidopsis hybrid.Genome biology · 2017Article
- Long Noncoding RNAs in Plants.Advances in experimental medicine and biology · 2017Review
- Light behind the curtain: photoregulation of nuclear architecture and chromatin dynamics in plants.The New phytologist · 2016Article
- Genome-wide analysis of chromatin packing in Arabidopsis thaliana at single-gene resolution.Genome research · 2016Article
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Authors and funding
9 authors.
Funding
Abstract
Vernalization, the promotion of flowering by cold, involves Polycomb-mediated epigenetic silencing of FLOWERING LOCUS C (FLC). Cold progressively promotes cell-autonomous switching to a silenced state. Here, we used live-cell imaging of FLC-lacO to monitor changes in nuclear organization during vernalization. FLC-lacO alleles physically cluster during the cold and generally remain so after plants are returned to warm. Clustering is dependent on the Polycomb trans-factors necessary for establishment of the FLC silenced state but not on LIKE HETEROCHROMATIN PROTEIN 1, which functions to maintain silencing. These data support the view that physical clustering may be a common feature of Polycomb-mediated epigenetic switching mechanisms.
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