ArticleMolecules (Basel, Switzerland)2013
Synthesis, evaluation of antioxidant activity and crystal structure of 2,4-dimethylbenzoylhydrazones.
Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties.Biomedicines · 2025Review
- Design synthesis, characterization, molecular docking and antimicrobial evaluation of novel heterocycles with acrylonitrile and anthracene moieties.Scientific reports · 2025Article
- Crystal structure of 4-[(4-methyl-benz-yl)-oxy]-Acta crystallographica. Section E, Crystallographic communications · 2023Article
- Bio-Oriented Synthesis of Novel (S)-Flurbiprofen Clubbed Hydrazone Schiff's Bases for Diabetic Management: In Vitro and In Silico Studies.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Synthesis, antibacterial and antioxidant activities of Thiazole-based Schiff base derivatives: a combined experimental and computational study.BMC chemistry · 2021Article
- Article
- Synthesis, biological evaluation of antioxidant-antibacterial activities and computational studies of novel anthracene- and pyrene-based Schiff base derivatives.Turkish journal of chemistry · 2020Article
- Design, Synthesis, Photophysical Properties, Biological Estimation and Molecular Docking Studies of Novel Schiff Base Derivatives as Potential Urease Inhibitors.Journal of fluorescence · 2018Article
- 2-Hydroxy-ACS omega · 2018Article
- Synthesis of novel bisindolylmethane Schiff bases and their antibacterial activity.Molecules (Basel, Switzerland) · 2014Article
- Phenoxyacetohydrazide Schiff bases: β-glucuronidase inhibitors.Molecules (Basel, Switzerland) · 2014Article
- Synthesis, crystal structure, DFT studies and evaluation of the antioxidant activity of 3,4-dimethoxybenzenamine schiff bases.Molecules (Basel, Switzerland) · 2014Article
- 2-{[2-(2-Hy-droxy-5-meth-oxy-benzyl-idene)hydrazin-1-yl-idene]meth-yl}-4-meth-oxy-phenol.Acta crystallographica. Section E, Structure reports online · 2014Article
- Synthesis of 4-methoxybenzoylhydrazones and evaluation of their antiglycation activity.Molecules (Basel, Switzerland) · 2014Article
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8 authors.
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Abstract
2,4-Dimethylbenzoylhydrazones 1-30 were synthesized by condensation reactions of 2,4-dimethylbenzoylhydrazide with various aromatic aldehydes and characterized. The assigned structures of compounds 10, 15 and 22 were further supported by single-crystal X-ray diffraction data. The synthesized compounds were evaluated for their in vitro DPPH radical scavenging activity. They exerted varying degree of scavenging activity toward DPPH radical with IC₅₀ values between 25.6-190 µM. Compounds 1, 4, 2, 3, 7, and 6 have IC₅₀ values of 25.6, 28.1, 29.3, 29.8, 30.0 and 30.1 µM respectively, showing better activity than an n-propyl gallate standard (IC₅₀ value = 30.30 µM). For super oxide anion scavenging activity compounds 1, 2 and 3 with IC₅₀ values of 98.3, 102.6, and 105.6, respectively, also showed better activity than the n-propyl gallate standard (IC₅₀ value = 106.34 µM).
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