ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2013
Myelomeningocele: the management of the associated hydrocephalus.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05711355 (A Randomized Trial of the Effects of Platelet-Rich Plasma on Postoperative Complications After Meningomyelocele Sac Repair), which is not on this map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Trial of the Effects of Platelet-Rich Plasma on Postoperative Complications After Meningomyelocele Sac Repair
Who cites it
27 citing papers in PubMed, 89 citations in OpenAlex.
- Myelomeningocele in Slovenia: An 18-Year National Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Ventriculovesical shunting in pediatric hydrocephalus with neurogenic bladder: a salvage case series and biomechanical considerations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- From birth to beyond: predicting incidence and timing of CSF diversion in postnatal MMC closure.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Endoscopic third ventriculostomy versus ventriculoperitoneal shunting for hydrocephalus treatment following prenatal and postnatal myelomeningocele repair.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Comprehensive assessment of supratentorial and infratentorial volumes in infants with myelomeningocele with and without Chiari malformation type II.Neuroradiology · 2025Article
- Concurrent myelomeningocele and sagittal craniosynostosis: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Revisiting the Pathophysiology of Intracranial Hemorrhage in Fetuses with Chiari II Malformation: Novel Imaging Biomarkers of Disease Severity?AJNR. American journal of neuroradiology · 2024Article
- Multiparametric prenatal imaging characterization of fetal brain edema in Chiari II malformation might help to select candidates for fetal surgery.European radiology · 2024Article
- Intracranial volumetric evaluation in postnatally repaired myelomeningocele infants.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Myelomeningocele: Long-Term Neurosurgical Management.Advances and technical standards in neurosurgery · 2024Review
- Spina bifida and cardiorespiratory profile: the impact of leisure sport activities on physical fitness.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Myelomeningocele: the evolution of care over the last 50 years.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Endoscopic third ventriculostomy for management of hydrocephalus associated with Chiari malformation type II in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- The impact of constant antibiotic prophylaxis in children affected by spinal dysraphism performing clean intermittent catheterization: a 2-year monocentric retrospective analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- External validation of the ETV success score in 313 pediatric patients: a Brazilian single-center study.Neurosurgical review · 2021Article
- Shunt timing in meningomyelocele and clinical results: analysis of 80 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Not all ventriculomegaly is created equal: diagnostic overview of fetal, neonatal and pediatric ventriculomegaly.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- A perspective in the management of myelomeningocoele in the KwaZulu-Natal Province of South Africa.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Observational
- Review on myelomeningocele management and its current status in Saudi Arabia.Neurosciences (Riyadh, Saudi Arabia) · 2019Review
- Experience in shunt management on revision free survival in infants with myelomeningocele.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe pathogenesis of the hydrocephalus associated with myelomeningocele (MMC) has been the subject of an extensive number of studies. The contemporary reduction of the incidence of the Chiari II malformation and of the associated active hydrocephalus after closure of the spinal defect in utero is in line with previous studies suggesting a prominent role of the posterior cranial fossa abnormalities, where even the increased venous pressure might be at least mostly a consequence of the constriction of the posterior cranial fossa structures. Pure absorptive abnormalities however coexist, the main ones documented to be abnormal cisternal spaces and peculiar cerebrospinal fluid chemical features. MATERIALS AND
methodsWe reviewed the pertinent literature concerning the pathogenesis and management of the hydrocephalus associated to MMC. We also reviewed our personal experience in managing the hydrocephalus in such patients through an endoscopic third ventriculostomy. RESULTS AND
conclusionsThe literature review demonstrated an overall reduction in more recent series of children with MMC needing to be treated for the associated hydrocephalus postnatally, questioning the role of the prenatal care of the disease in this context. Less severe conditions and a more conservative neurosurgical attitude have certainly contributed to the reduction of the reported active postnatal hydrocephalus rate. Long-term cognitive evaluation of the children with MMC that we managed with an endoscopic third ventriculocisternostomy (ETV) as primary as well as secondary procedure did not demonstrate significant differences in the outcome compared with non-complicated extrathecally shunted children, favouring ETV as a valuable option in this subset of patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.