Evidence map›Paper›PMID 24012365›Full record

ArticleCell stem cell2013

And then there were none: no need for pluripotency factors to induce reprogramming.

Bin-Kuan Chou, Linzhao Cheng

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell stem cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Epigenetic regulation of open chromatin in pluripotent stem cells.Translational research : the journal of laboratory and clinical medicine · 2015
    Review
  6. DLK1-DIO3 imprinted cluster in induced pluripotency: landscape in the mist.Cellular and molecular life sciences : CMLS · 2014
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Bin-Kuan ChouStem Cell Program in the Institute for Cell Engineering and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Linzhao Cheng

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI Rosalie Wollett · 1985 to 2026
$208.6M
NCI NIH HHS P30 CA006973
6 · The paper itself

Abstract

While most factors used as reprogramming transgenes can be replaced by other means, Oct4 has remained essential until now. Three recent papers have now broken this barrier through the use of opposing lineage specifying transgenes and chemical modulation, thus signifying a milestone in advancing our understanding of pluripotency induction.

Indexed as

Cell DedifferentiationAnimalsCell EngineeringCellular ReprogrammingFibroblastsGATA3 Transcription FactorHumansInduced Pluripotent Stem CellsOctamer Transcription Factor-3Pluripotent Stem CellsSmall Molecule LibrariesTranscription FactorsGATA3 protein, humanGATA3 Transcription FactorOctamer Transcription Factor-3POU5F1 protein, humanSmall Molecule LibrariesTranscription Factors

Identifiers

PMID24012365
PMCPMC4659384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.