Evidence map›Paper›PMID 24011986›Full record

ArticleDrug and alcohol dependence2013

Effects of working memory load, a history of conduct disorder, and sex on decision making in substance dependent individuals.

Daniel J Fridberg, Kyle R Gerst, Peter R Finn

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Intelligence moderates the relationship between delay discounting rate and problematic alcohol use.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
    Article
  4. Article
  5. Article
  6. Let's call the whole thing off: evaluating gender and sex differences in executive function.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Review
  7. Delay discounting of losses and rewards in alcohol use disorder: The effect of working memory load.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. The Effects of a Working Memory Load on Delay Discounting in Those with Externalizing Psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2015
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel J FridbergDepartment of Psychological and Brain Sciences, Indiana University Bloomington, 1101 East 10th Street, Bloomington, IN 47405, USA.
Kyle R Gerst
Peter R Finn
Indiana University Bloomington · US

Funding

TRAINING GRANT ON GENETICS ASPECTS OF ALCOHOLISMT32AA007462 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CRISTINE L CZACHOWSKI · 1985 to 2026
$10.7M
Behavioral Disinhibition in Early-onset AlcoholismR01AA013650 · NIAAA · TRUSTEES OF INDIANA UNIVERSITY · PI FINN, PETER R · 2002 to 2018
$5.5M
NIAAA NIH HHS R01 AA013650NIAAA NIH HHS R01 AA13650NIAAA NIH HHS T32 AA007462NIAAA NIH HHS T32 AA007462-26
6 · The paper itself

Abstract

backgroundSubstance dependence and antisocial psychopathology, such as a history of childhood conduct disorder (HCCD), are associated with impulsive or disadvantageous decision making and reduced working memory capacity (WMC). Reducing WMC via a working memory load increases disadvantageous decision making in healthy adults, but no previous studies have examined this effect in young adults with substance dependence and HCCD.

methodYoung adults with substance dependence (SubDep; n=158, 71 female), substance dependence and HCCD (SubDep+HCCD; n=72, 24 female), and control participants (n=152, 84 female) completed a test of decision making (the Iowa Gambling Task; IGT) with or without a concurrent working memory load intended to tax WMC. Outcomes were (i) net advantageous decisions on the IGT, and (ii) preferences for infrequent- versus frequent-punishment decks.

resultsSubDep+HCCD men made fewer advantageous decisions on the IGT than control men without a load, but there were no group differences among women in that condition. Load was associated with fewer advantageous decisions for SubDep+HCCD women and control men, but not for men or women in the other groups. Participants showed greater preference for infrequent-punishment, advantageous decks under load as well.

conclusionsThere are gender differences in the effects of substance dependence, HCCD, and working memory load on decision making on the IGT. Decision making by control men and SubDep+HCCD women suffered the most under load. Load increases preferences for less-frequent punishments, similar to a delay discounting effect. Future research should clarify the cognitive and neural mechanisms underlying these effects.

Indexed as

AdolescentAdultAlcoholismAnalysis of VarianceConduct DisorderDecision MakingFemaleHumansImpulsive BehaviorIntelligence TestsMaleMarijuana AbuseMemory, Short-TermNeuropsychological TestsPunishmentReinforcement ScheduleConduct disorderDecision-makingSubstance dependenceWorking memory capacity

Identifiers

PMID24011986
PMCPMC3818396
OpenAlexW2053914379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.