Evidence map›Paper›PMID 24011890›Full record

ReviewEndocrinology and metabolism clinics of North America2013

Sleep disorders and the development of insulin resistance and obesity.

Omar Mesarwi, Jan Polak, Jonathan Jun, Vsevolod Y Polotsky

Registry-linked trialAbstract readReview
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04780828 (Investigation of the Effects of Different Obesity Levels on the Respiratory System), which is not on this map. Cited by 63 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 5 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04780828 completednot on this mapstarted 2020, after this paper: background citation

Investigation of the Effects of Different Obesity Levels on the Respiratory System: In Our Study, Besides the Effect of Obesity on the Respiratory System, Many Different Parameters Related to Health Will be Compared.

TypeobservationalSponsorIstanbul Medipol University HospitalRan2020 to 2021Enrolled100ConditionsObesity, Adolescent, Obesity, Morbid, Obesity, Abdominal, Obesity, Visceral
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 5 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Association Between Serum Trace Elements and Obstructive Sleep Apnea in Iranian Adults: Multiple-exposure Models.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
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  15. The association between sleep fragmentation and incident atrial fibrillation: a prospective cohort study in a community population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Omar MesarwiDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA.
Jan Polak
Jonathan Jun
Vsevolod Y Polotsky
Johns Hopkins University · US

Funding

JHU-UMD Diabetes Research CenterP30DK079637 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI BRANCATI, FREDERICK L · 2013 to 2017
$9.7M
Sleep Apnea and Dysregulation of Lipid MetabolismR01HL080105 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI POLOTSKY, VSEVOLOD Y · 2005 to 2014
$3.4M
Mechanisms and Consequences of Intermittent Hypoxia-Induced LipolysisK08HL109475 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI JUN, JONATHAN C. · 2012 to 2016
$725k
NHLBI NIH HHS HL080105NHLBI NIH HHS HL109475NHLBI NIH HHS K08 HL109475NHLBI NIH HHS R01 HL080105NIDDK NIH HHS P30 DK079637
6 · The paper itself

Abstract

Normal sleep is characterized both by reduced glucose turnover by the brain and other metabolically active tissues, and by changes in glucose tolerance. Sleep duration has decreased over the last several decades; data suggest a link between short sleep duration and type 2 diabetes. Obstructive sleep apnea (OSA) results in intermittent hypoxia and sleep fragmentation, and also is associated with impaired glucose tolerance. Obesity is a major risk factor for OSA, but whether OSA leads to obesity is unclear. The quality and quantity of sleep may profoundly affect obesity and glucose tolerance, and should be routinely assessed by clinicians.

Indexed as

Circadian RhythmGlucose IntoleranceHumansInsulin ResistanceObesitySleep Wake DisordersDiabetesGlucose homeostasisMetabolismObstructive sleep apneaSleep duration

Identifiers

PMID24011890
PMCPMC3767932
OpenAlexW2064091347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.