Evidence map›Paper›PMID 24011516›Full record

ReviewCurrent opinion in pharmacology2013

Antifungal therapy with an emphasis on biofilms.

Christopher G Pierce, Anand Srinivasan, Priya Uppuluri, Anand K Ramasubramanian, José L López-Ribot

Abstract readReview
In one paragraph

Review in Current opinion in pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Repositioning Antimicrobial Peptides Against WHO-Priority Fungi.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  7. Article
  8. Myricetin Exerts Antibiofilm Effects onJournal of fungi (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cold atmospheric plasma inactivatesJournal of medical microbiology · 2024
    Article
  15. Article
  16. Antifungal activity against Candida albicans of methyl 3,5-dinitrobenzoate loaded nanoemulsion.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  17. Article
  18. Antifungal therapy ofBiofilm · 2023
    Article
  19. Antifungal Activity and Type of Interaction ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher G PierceDepartment of Biology, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA; South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.
Anand Srinivasan
Priya Uppuluri
Anand K Ramasubramanian
José L López-Ribot

Funding

Targeting virulence against oral candidiasis in HIV/AIDSR01DE023510 · NIDCR · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L. · 2013 to 2017
$1.8M
NIDCR NIH HHS 1R01DE023510-01NIDCR NIH HHS R01 DE023510
6 · The paper itself

Abstract

Fungal infections are on the rise as advances in modern medicine prolong the lives of severely ill patients. Fungi are eukaryotic organisms and there are a limited number of targets for antifungal drug development; as a result the antifungal arsenal is exceedingly limited. Azoles, polyenes and echinocandins constitute the mainstay of antifungal therapy for patients with life-threatening mycoses. One of the main factors complicating antifungal therapy is the formation of fungal biofilms, microbial communities displaying resistance to most antifungal agents. A better understanding of fungal biofilms provides for new opportunities for the development of urgently needed novel antifungal agents and strategies.

Indexed as

AnimalsAntifungal AgentsBiofilmsDrug Resistance, FungalFungiHumansMycosesAntifungal Agents

Identifiers

PMID24011516
PMCPMC3795934

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.