ArticleThe journal of evidence-based dental practice2013
Xylitol lozenges were not effective in overall dental caries prevention in adults.
Article in The journal of evidence-based dental practice, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed, 2 citations in OpenAlex.
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Funding
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Abstract
article title and bibliographic informationResults from the xylitol for adult caries trial (X-ACT). Bader JD, Vollmer WM, Shugars DA, Gilbert GH, Amaechi BT, Brown JP, Laws RL, Kunkhouser KA, Makhija SK, Ritter AV, Leo MC. JADA 2013; 144(1): 21-30. REVIEWERS: Margherita Fontana, DDS, PhD, Carlos Gonzalez-Cabezas, DDS, MSD, PhD PURPOSE/QUESTION: Among an adult population at risk of dental caries, does the use of five 1 g xylitol lozenges per day over 33 months reduce the experience of cavitated caries lesions? SOURCE OF
fundingGovernment: National Institute of Dental and Craniofacial Research TYPE OF STUDY/
designMulticenter, double blind, placebo-controlled, randomized clinical trial LEVEL OF EVIDENCE: Level 1: Good quality, patient-oriented evidence STRENGTH OF RECOMMENDATION GRADE: B: Limited quality patient-oriented evidence.
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