ArticleBiophysical journal2013
Coexistence of fluid and crystalline phases of proteins in photosynthetic membranes.
Article in Biophysical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Unraveling design principles of protein landscapes in photosynthetic membranes in plant chloroplasts.Science advances · 2026Article
- Lighting the way: Compelling open questions in photosynthesis research.The Plant cell · 2024Article
- Energetic driving force for LHCII clustering in plant membranes.Science advances · 2023Article
- A Chloroplast-Localised Fluorescent Protein Enhances the Photosynthetic Action Spectrum in Green Algae.Microorganisms · 2022Article
- Temperature-dependent regulation of electron transport and ATP synthesis in chloroplasts in vitro and in silico.Photosynthesis research · 2020Article
- Modeling the Role of LHCII-LHCII, PSII-LHCII, and PSI-LHCII Interactions in State Transitions.Biophysical journal · 2020Article
- Lattice Models for Protein Organization throughout Thylakoid Membrane Stacks.Biophysical journal · 2020Article
- Molecular dynamics simulations in photosynthesis.Photosynthesis research · 2020Review
- Fine-tuning the photosynthetic light harvesting apparatus for improved photosynthetic efficiency and biomass yield.Scientific reports · 2019Article
- Models and mechanisms of the rapidly reversible regulation of photosynthetic light harvesting.Open biology · 2019Review
- Energy-dependent quenching adjusts the excitation diffusion length to regulate photosynthetic light harvesting.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Multiscale model of light harvesting by photosystem II in plants.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- The Use of Contact Mode Atomic Force Microscopy in Aqueous Medium for Structural Analysis of Spinach Photosynthetic Complexes.Plant physiology · 2015Article
- Article
- Models and measurements of energy-dependent quenching.Photosynthesis research · 2013Review
- Coarse-grained computer simulation of dynamics in thylakoid membranes: methods and opportunities.Frontiers in plant science · 2013Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photosystem II (PSII) and its associated light-harvesting complex II (LHCII) are highly concentrated in the stacked grana regions of photosynthetic thylakoid membranes. PSII-LHCII supercomplexes can be arranged in disordered packings, ordered arrays, or mixtures thereof. The physical driving forces underlying array formation are unknown, complicating attempts to determine a possible functional role for arrays in regulating light harvesting or energy conversion efficiency. Here, we introduce a coarse-grained model of protein interactions in coupled photosynthetic membranes, focusing on just two particle types that feature simple shapes and potential energies motivated by structural studies. Reporting on computer simulations of the model's equilibrium fluctuations, we demonstrate its success in reproducing diverse structural features observed in experiments, including extended PSII-LHCII arrays. Free energy calculations reveal that the appearance of arrays marks a phase transition from the disordered fluid state to a system-spanning crystal. The predicted region of fluid-crystal coexistence is broad, encompassing much of the physiologically relevant parameter regime; we propose experiments that could test this prediction. Our results suggest that grana membranes lie at or near phase coexistence, conferring significant structural and functional flexibility to this densely packed membrane protein system.
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