Evidence map›Paper›PMID 24009793›Full record

ArticleElectronic journal of statistics2013

Deconvolution estimation of mixture distributions with boundaries.

Mihee Lee, Peter Hall, Haipeng Shen, J S Marron, Jon Tolle, Christina Burch

Abstract read
In one paragraph

Article in Electronic journal of statistics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mihee LeeDepartment of Mathematics and Statistics, University of Melbourne, Parkville, VIC, Australia, miheel@unimelb.edu.au.
Peter Hall
Haipeng Shen
J S Marron
Jon Tolle
Christina Burch

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHARLES M PEROU · 1992 to 2026
$59.3M
Conserved Biology of Tumor and Microenvironment in Breast Cancer ProgressionR01CA138255 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEROU, CHARLES M, TROESTER, MELISSA A. · 2008 to 2012
$2.4M
Viral evolution:mutational effects and interactionsR01GM067940 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BURCH, CHRISTINA L. · 2003 to 2007
$711k
NCI NIH HHS P30 CA016086NCI NIH HHS P50 CA058223NCI NIH HHS R01 CA138255NIGMS NIH HHS R01 GM067940
6 · The paper itself

Abstract

In this paper, motivated by an important problem in evolutionary biology, we develop two sieve type estimators for distributions that are mixtures of a finite number of discrete atoms and continuous distributions under the framework of measurement error models. While there is a large literature on deconvolution problems, only two articles have previously addressed the problem taken up in our article, and they use relatively standard Fourier deconvolution. As a result the estimators suggested in those two articles are degraded seriously by boundary effects and negativity. A major contribution of our article is correct handling of boundary effects; our method is asymptotically unbiased at the boundaries, and also is guaranteed to be nonnegative. We use roughness penalization to improve the smoothness of the resulting estimator and reduce the estimation variance. We illustrate the performance of the proposed estimators via our real driving application in evolutionary biology and two simulation studies. Furthermore, we establish asymptotic properties of the proposed estimators.

Indexed as

Boundary effectmaximum likelihoodmeasurement errormixture distributionpenalizationsieve method

Identifiers

PMID24009793
PMCPMC3759521

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.