SynthesisPloS one2013
Representation of women and pregnant women in HIV research: a limited systematic review.
Synthesis in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Ethical considerations for research involving pregnant women living with HIV and their young children: a systematic review of the empiric literature and discussion.BMC medical ethics · 2021Pooled it
- HIV Risk Reduction Interventions Among Substance-Abusing Reproductive-Age Women: A Systematic Review.AIDS education and prevention : official publication of the International Society for AIDS Education · 2017Pooled it
- Divergent Burden Profiles of HIV/AIDS and Other Sexually Transmitted Infections Among Women of Child-Bearing Age, 1990-2021.International journal of women's health · 2026Article
- Substance Use and Drug Treatment Among Reproductive-Age Women With and Without HIV in the Southern United States.Open forum infectious diseases · 2025Article
- Pre-exposure prophylaxis in the perinatal period.The lancet. HIV · 2024Article
- Study of Treatment and Reproductive Outcomes Among Reproductive-Age Women With HIV Infection in the Southern United States: Protocol for a Longitudinal Cohort Study.JMIR research protocols · 2021Article
- Screening and Enrollment by Sex in Human Immunodeficiency Virus Clinical Trials in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- Viraemia before, during and after pregnancy in HIV-infected women on antiretroviral therapy in rural KwaZulu-Natal, South Africa, 2010-2015.Tropical medicine & international health : TM & IH · 2018Article
- A qualitative study on acceptable levels of risk for pregnant women in clinical research.BMC medical ethics · 2017Article
- Advancing HIV research with pregnant women: navigating challenges and opportunities.AIDS (London, England) · 2016Article
- How do outcomes compare between women and men living with HIV in Australia? An observational study.Sexual health · 2016Observational
- Women in HIV cure research: multilevel interventions to improve sex equity in recruitment.Journal of virus eradicationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundHIV-related outcomes may be affected by biological sex and by pregnancy. Including women in general and pregnant women in particular in HIV-related research is important for generalizability of findings.
objectiveTo characterize representation of pregnant and non-pregnant women in HIV-related research conducted in general populations. DATA SOURCES: All HIV-related articles published in fifteen journals from January to March of 2011. We selected the top five journals by 2010 impact factor, in internal medicine, infectious diseases, and HIV/AIDS. STUDY ELIGIBILITY CRITERIA: HIV-related studies reporting original research on questions applicable to both men and women of reproductive age were considered; studies were excluded if they did not include individual-level patient data. STUDY APPRAISAL AND SYNTHESIS
methodsArticles were doubly reviewed and abstracted; discrepancies were resolved through consensus. We recorded proportion of female study participants, whether pregnant women were included or excluded, and other key factors.
resultsIn total, 2014 articles were published during this period. After screening, 259 articles were included as original HIV-related research reporting individual-level data; of these, 226 were determined to be articles relevant to both men and women of reproductive age. In these articles, women were adequately represented within geographic region. The vast majority of published articles, 183/226 (81%), did not mention pregnancy (or related issues); still fewer included pregnant women (n=33), reported numbers of pregnant women (n=19), or analyzed using pregnancy status (n=9). LIMITATIONS: Data were missing for some key variables, including pregnancy. The time period over which published works were evaluated was relatively short. CONCLUSIONS AND IMPLICATIONS OF KEY
findingsThe under-reporting and inattention to pregnancy in the HIV literature may reduce policy-makers' ability to set evidence-based policy around HIV/AIDS care for pregnant women and women of child-bearing age.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.