Evidence map›Paper›PMID 24009673›Full record

ArticlePloS one2013

Syphilis screening among 27,150 pregnant women in South Chinese rural areas using point-of-care tests.

Li-Gang Yang, Joseph D Tucker, Feng-Ying Liu, Xu-Qi Ren, Xuan Hong, Cheng Wang, Megan M McLaughlin, Cedric H Bien, Xiang-Sheng Chen, Bin Yang

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Introduction of rapid syphilis testing in antenatal care: A systematic review of the impact on HIV and syphilis testing uptake and coverage.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2015
    Pooled it
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  15. Synthesized prevention and control of one decade for mother-to-child transmission of syphilis and determinants associated with congenital syphilis and adverse pregnancy outcomes in Shenzhen, South China.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li-Gang YangDivision of STD Control, Guangdong Provincial Center for STI & Skin Diseases Control and Prevention, Guangzhou, China. yanglg3@yahoo.com
Joseph D Tucker
Feng-Ying Liu
Xu-Qi Ren
Xuan Hong
Cheng Wang
Megan M McLaughlin
Cedric H Bien
Xiang-Sheng Chen
Bin Yang

Funding

UNC-South China STD Research Training CenterD43TW009532 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COHEN, MYRON SCOTT, TUCKER, JOSEPH DAVID · 2013 to 2017
$1.3M
Syphilis social epidemiology in the People's Republic of ChinaK01TW008200 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI TUCKER, JOSEPH DAVID · 2010 to 2013
$527k
FIC NIH HHS 1K01TW008200-01A1FIC NIH HHS D43 TW009532FIC NIH HHS K01 TW008200
6 · The paper itself

Abstract

objectivesTo determine the prevalence and correlates of syphilis among pregnant women in rural areas of South China.

methodsPoint-of-care syphilis testing was provided at 71 health facilities in less developed, rural areas of Guangdong Province. Positive samples were confirmed at a local referral center by toluidine red unheated serum tests (TRUST) and Treponema pallidum particle agglutination (TPPA) tests.

resultsAltogether 27,150 pregnant women in rural Guangdong were screened for syphilis. 106 (0.39%) syphilis cases were diagnosed, of which 78 (73.6%) received treatment for syphilis. Multivariate analysis revealed that older pregnant women (31-35 years old, aOR 2.7, 95% CI 0.99-7.32; older than 35 years old, aOR 5.9, 95% CI 2.13-16.34) and those with a history of adverse pregnant outcomes (aOR 3.64, 95% CI 2.30-5.76) were more likely to be infected with syphilis.

conclusionsA high prevalence of syphilis exists among pregnant women living in rural areas of South China. Enhanced integration of syphilis screening with other routine women's health services (OB GYN, family planning) may be useful for controlling China's syphilis epidemic.

Indexed as

Mass ScreeningPoint-of-Care SystemsRural PopulationAdolescentAdultChinaFemaleHumansMiddle AgedPregnancyPrevalenceRisk FactorsSyphilisYoung Adult

Identifiers

PMID24009673
PMCPMC3756989

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.