Evidence map›Paper›PMID 24009649›Full record

ArticleJournal of mental health research in intellectual disabilities2008

Mood and Anxiety Symptoms in Psychiatric Inpatients with Autism Spectrum Disorder and Depression.

Lauren Charlot, Curtis K Deutsch, Aranya Albert, Anne Hunt, Daniel F Connor, William J McIlvane

Abstract read
In one paragraph

Article in Journal of mental health research in intellectual disabilities, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Treatment of Adults with Autism and Major Depressive Disorder Using Transcranial Magnetic Stimulation: An Open Label Pilot Study.Autism research : official journal of the International Society for Autism Research · 2020
    Article
  9. Article
  10. Depression in Youth with Autism Spectrum Disorder.Child and adolescent psychiatric clinics of North America · 2019
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Lauren CharlotDepartment of Psychiatry University of Massachusetts Medical School.
Curtis K Deutsch
Aranya Albert
Anne Hunt
Daniel F Connor
William J McIlvane
University of Massachusetts Chan Medical School · USEunice Kennedy Shriver Center · USUniversity of Connecticut · US

Funding

TISSUE CULTURE CORE FACILITYP30HD004147 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCILVANE, WILLIAM J · 1985 to 2014
$9.1M
Behavioral Studies of Mental Retardation and DepressionR01HD042807 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCILVANE, WILLIAM J · 2004 to 2007
$1.3M
NICHD NIH HHS P30 HD004147NICHD NIH HHS R01 HD042807
6 · The paper itself

Abstract

Recent reports suggest that individuals with autism spectrum disorders (ASD) may experience depression at a high frequency, yet few published studies address this issue, especially among adults. In the current investigation, we reviewed features of depression and comorbid traits among depressed inpatients with intellectual disabilities (ID) as a function of ASD. A retrospective chart review was performed for 53 inpatients meeting criteria for depression (13 individuals with ASD and ID and 40 matched individuals with ID but without ASD), all of whom had received a diagnosis of depression at the time of discharge from a specialty psychiatric unit for adults with ID. The depression diagnoses were based on a comprehensive clinical assessment; specific mood and anxiety symptoms were reported by informants at the time of intake using the Mood and Anxiety Semi-Structured (MASS) Interview for Patients with Intellectual Disabilities (Charlot, Deutsch, Hunt, Fletcher, & McIlvane, 2007). Overall, few qualitative differences were detected between the 2 groups. Both depressed inpatient groups had high rates of comorbid anxiety disorders as well as externalizing behaviors. Inpatients with ASD had a total of 2 more symptoms (out of 29 possible symptom items) than their depressed peers without an ASD diagnosis (mean scores of 12.23 and 9.85, respectively). Anxiety disorders were reported in 62% of individuals with ASD and 38% of those without ASD. Antipsychotic medication was prevalent among the patients with ASD and depression. Over 80% of the inpatients with ASD and depression, compared with 49% of the non-ASD group, were treated with these medications.

Indexed as

antipsychotic medicationsanxietyautismautism spectrum disordersdepressionmood disorders

Identifiers

PMID24009649
PMCPMC3760522
OpenAlexW2070936959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.