Evidence map›Paper›PMID 24009640›Full record

ArticleClinical practice and epidemiology in mental health : CP & EMH2013

Physical activity in depressed elderly. A systematic review.

Gioia Mura, Mauro Giovanni Carta

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical practice and epidemiology in mental health : CP & EMH, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03858114 (Active Ageing and Health), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03858114 nacompletednot on this mapstarted 2019, after this paper: background citation

Active Ageing and Health

TypeinterventionalSponsorUniversity of CagliariRan2019 to 2020Enrolled140ConditionsAging, Chronic Disease, Cognitive Decline, Quality of LifeArmsMild-to-moderate physical activity, Cultural group program
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 131 citations in OpenAlex.

  1. Pooled it
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  5. Remission is insufficient: predictors and mechanistic models of recurrence in late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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  14. Sleep, physical activity, and sedentary behaviors as factors related to depression and health-related quality of life among older women living alone: a population-based study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023
    Article
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Gioia MuraDepartment of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy.
Mauro Giovanni Carta
Bentham Science Publishers (United Arab Emirates)University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundexercise may reduce depressive symptoms both in healthy aged populations and in old patients diagnosed with MDD, but few specific analysis were conducted on the efficacy of exercise as an adjunctive treatment with antidepressants, which may be probably more useful in clinical practice, considered the high prevalence of treatment resistant depression in late life, the low cost and safety of physical activity interventions.

objectiveto establish the new findings on the effectiveness of exercise on depression in elderlies, with particular focus on the efficacy of the exercise as an adjunctive treatment with antidepressants drug therapy.

methodTHE SEARCH OF SIGNIFICANT ARTICLES WAS CARRIED OUT IN PUBMED/MEDLINE WITH THE FOLLOWING KEY WORDS: "exercise", "physical activity", "physical fitness", "depressive disorder", "depression", "depressive symptoms", "late life", "old people", and "elderly".

results44 papers were retrieved by the search. Among the 10 included randomized controlled trials, treatment allocation was adequately conceived in 4 studies, intention-to-treat analysis was performed in 6 studies, but no study had a double-blinded assessment. We examined and discussed the results of all these trials.

conclusionin the last 20 years, few progresses were done in showing the efficacy of exercise on depression, due in part to the persistent lack of high quality research, in part to clinical issues of management of depression in late life, in part to the difficult to establish the real effectiveness of exercise on depressive symptoms in elderlies. However, there are some promising findings on physical activity combined with antidepressants in treatment resistant late life depression.

Indexed as

DepressionelderlyExerciseLate lifeMood disorderPhysical activitySystematic review.

Identifiers

PMID24009640
PMCPMC3758953
OpenAlexW2037295038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.