Evidence map›Paper›PMID 24009246›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2013

The surgically induced stress response.

Celeste C Finnerty, Nigel Tapiwa Mabvuure, Arham Ali, Rosemary A Kozar, David N Herndon

2 registry-linked trialsAbstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 194 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05520151 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Influence of Preoperative Immunomodulation by Oral Impact® on Postoperative Complications Following Cystectomies and Nephrectomies

TypeinterventionalSponsorCentre Hospitalier Intercommunal Robert BallangerRan2022 to 2025Enrolled214ConditionsUrological ManifestationsArmsORAL IMPACT treatment, control
NCT06516861 phase1completednot on this mapstarted 2024, after this paper: background citation

Comparison of Magnesium Sulphate 30 mg/Kg With Lidocaine 1,5 mg/Kg in Hemodynamic Changes and Cortisol Level Post-intubation in Patient Undergoing Craniotomy

TypeinterventionalSponsorArsil RadiansyahRan2024 to 2024Enrolled30ConditionsIntubation ComplicationArmsMagnesium Sulfate 20 MG/ML, Lidocaine IV, saline solution
3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  20. Effect of total gastrectomy on weight and body composition: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article

134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Celeste C FinnertyDepartment of Surgery, Shriners Hospitals for Children-Galveston and the University of Texas Medical Branch, Galveston, Texas.
Nigel Tapiwa Mabvuure
Arham Ali
Rosemary A Kozar
David N Herndon

Funding

Project 9: The role of androgen/corticosteroid in fat, muscle and glucose metabolism of burn victimsP50GM060338 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI SZABO, CSABA · 2000 to 2017
$24.2M
UTMB CLINICAL AND TRANSLATIONAL SCIENCE AWARD: NASA BED REST STUDIESUL1RR029876 · NCRR · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BRASIER, ALLAN R. · 2009 to 2011
$17.7M
MODULATION OF THE POSTBURN HYPERMETABOLIC RESPONSER01GM056687 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI HERNDON, DAVID N. · 1998 to 2017
$9.0M
POSTDOCTORAL TRAINING IN TRAUMA &BURNST32GM008256 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Celeste Campbell Finnerty, Oscar E. Suman-Vejas · 1990 to 2026
$4.0M
UTMB Clinical and Translational Science AwardKL2RR029875 · NCRR · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BRASIER, ALLAN R. · 2009 to 2011
$609k
NCRR NIH HHS KL2 RR029875NCRR NIH HHS KL2RR029875NCRR NIH HHS UL1 RR029876NCRR NIH HHS UL1RR029876NIGMS NIH HHS P50 GM060338NIGMS NIH HHS P50-GM60338NIGMS NIH HHS R01 GM056687NIGMS NIH HHS R01-GM56687NIGMS NIH HHS T32 GM008256NIGMS NIH HHS T32-GM8256PHS HHS H133A070026PHS HHS H133A70019
6 · The paper itself

Abstract

The stress response to surgery, critical illness, trauma, and burns encompasses derangements of metabolic and physiological processes that induce perturbations in the inflammatory, acute phase, hormonal, and genomic responses. Hypermetabolism and hypercatabolism result, leading to muscle wasting, impaired immune function and wound healing, organ failure, and death. The surgery-induced stress response is largely similar to that triggered by traumatic injuries; the duration of the stress response, however, varies according to the severity of injury (surgical or traumatic). This spectrum of injuries and insults ranges from small lacerations to severe insults such as large poly-traumatic and burn injuries. Burn injuries provide an extreme model of trauma induced stress responses that can be used to study the long-term effects of a prolonged stress response. Although the stress response to acute trauma evolved to confer improved chances of survival following injury, in modern surgical practice the stress response can be detrimental.

Indexed as

Critical IllnessStress, PhysiologicalBurnsGrowth HormoneHumansHydrocortisoneInflammationMuscular DiseasesSurgical Procedures, OperativeVasopressinsWound HealingWounds and InjuriesGrowth HormoneHydrocortisoneVasopressinsburnsnutrition therapyresponse to injurystress metabolismsurgical stress

Identifiers

PMID24009246
PMCPMC3920901

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.