ArticleCerebral cortex (New York, N.Y. : 1991)2015
Spatial olfactory learning contributes to place field formation in the hippocampus.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Olfactory spatial memory: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- A neural circuit of food sight-promoted feeding and contextual memory in mice.Nature communications · 2026Article
- A deep reinforcement learning account of competition and integration of visual and goal vector signals for spatial navigation.Scientific reports · 2026Article
- Discrete and differentiated encoding of distinct components of spatial experience occurs within the proximodistal subfields of the dorsoventral axis of the hippocampus.Frontiers in behavioral neuroscience · 2026Article
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
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- How do mammals convert dynamic odor information into neural maps for landscape navigation?PLoS biology · 2024Article
- Distal but not local auditory information supports spatial representations by place cells.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Hippocampal sequences span experience relative to rewards.bioRxiv : the preprint server for biology · 2024Article
- An experimental framework for conjoint measures of olfaction, navigation, and motion as pre-clinical biomarkers of Alzheimer's disease.Journal of Alzheimer's disease reports · 2024Review
- Neurosustainability.Frontiers in human neuroscience · 2024Article
- Recruitment of grid-like responses in human entorhinal and piriform cortices by odor landmark-based navigation.Current biology : CB · 2023Article
- The medial entorhinal cortex is necessary for the stimulus control over hippocampal place fields by distal, but not proximal, landmarks.Hippocampus · 2023Article
- Aging differentially affects LTCC function in hippocampal CA1 and piriform cortex pyramidal neurons.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The PROUST hypothesis: the embodiment of olfactory cognition.Animal cognition · 2023Review
- Role of mGlu5 in Persistent Forms of Hippocampal Synaptic Plasticity and the Encoding of Spatial Experience.Cells · 2022Review
- Lifelong changes of neurotransmitter receptor expression and debilitation of hippocampal synaptic plasticity following early postnatal blindness.Scientific reports · 2022Article
- How the evolution of air breathing shaped hippocampal function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Spatial encoding in the hippocampus is multifactorial, and it is well established that metric information about space is conferred by place cells that fire when an animal finds itself in a specific environmental location. Visuospatial contexts comprise a key element in the formation of place fields. Nevertheless, hippocampus does not only use visual cues to generate spatial representations. In the absence of visual input, both humans and other vertebrates studied in this context, are capable of generating very effective spatial representations. However, little is known about the relationship between nonvisual sensory modalities and the establishment of place fields. Substantial evidence exists that olfactory information can be used to learn spatial contexts. Here, we report that learning about a distinct odor constellation in an environment, where visual and auditory cues are suppressed, results in stable place fields that rotate when the odor constellations are rotated and remap when the odor constellations are shuffled. These data support that the hippocampus can use nonvisuospatial resources, and specifically can use spatial olfactory information, to generate spatial representations. Despite the less precise nature of olfactory stimuli compared with visual stimuli, these can substitute for visual inputs to enable the acquisition of metric information about space.
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