Evidence map›Paper›PMID 24006935›Full record

ReviewMolecular cancer2013

The complexity of bladder cancer: long noncoding RNAs are on the stage.

Quanan Zhang, Mo Su, Guangming Lu, Jiangdong Wang

Abstract readReview
In one paragraph

Review in Molecular cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  11. Review
  12. Role of Long Non-coding RNAs on Bladder Cancer.Frontiers in cell and developmental biology · 2021
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. CARLo-7-A plausible biomarker for bladder cancer.International journal of experimental pathology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Quanan ZhangDepartment of Pathology, Laboratory of Molecular Pathology and Molecular Imaging, Jinling Hospital, School of Medicine Nanjing University, 305 Zhong Shan Dong Lu, 210002 Nanjing, China. wangjd@aliyun.com.
Mo Su
Guangming Lu
Jiangdong Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian genome encodes thousands of long noncoding RNAs (lncRNAs) and it is increasingly clear that lncRNAs are key regulators of cellular function and development. Gain and/or loss of function studies in cell culture indicate that lncRNAs can regulate gene transcription indirectly through the targeting and recruitment of chromatin-modifying complexes as well as directly at the transcriptional or posttranscriptional levels. LncRNA biology is attracting great attention in cancer research because dysregulated lncRNAs occur in a variety of cancers, placing lncRNAs on the stage of cancer genome research. We briefly describe the latest lncRNA biology and discuss the oncogenic lncRNAs involved in core pathways in bladder cancer and the application of lncRNAs to its diagnosis and targeted treatment. LncRNAs are becoming essential components of the gene regulatory circuitry in the complexity of bladder cancer.

Indexed as

AnimalsGene ExpressionGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansRNA, Long NoncodingSignal TransductionUrinary Bladder NeoplasmsRNA, Long Noncoding

Identifiers

PMID24006935
PMCPMC3846905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.