Evidence map›Paper›PMID 24006467›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2013

Type IV pili in Gram-positive bacteria.

Stephen Melville, Lisa Craig

Open access · bronzeAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 218 citations in OpenAlex.

  1. Review
  2. Article
  3. Type IV pilin regulation: a transcriptional overview.Critical reviews in microbiology · 2026
    Review
  4. Article
  5. Resolving taxonomic uncertainties in the genusFrontiers in microbiology · 2026
    Article
  6. Article
  7. International journal of molecular sciences · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Separation ofmBio · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Type IV pili ofEcoSal Plus · 2024
    Review
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Stephen MelvilleDepartment of Biological Sciences, Virginia Tech, Blacksburg, Virginia, USA. melville@vt.edu
Lisa Craig
Simon Fraser University · CAVirginia Tech · US

Funding

Proteomic Analyses of Clostridium difficile Spore Germination ApparatusR21AI088298 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI HELM, RICHARD, JENSEN, RODERICK V · 2010 to 2011
$410k
NIAID NIH HHS R21 AI088298
6 · The paper itself

Abstract

Type IV pili (T4P) are surface-exposed fibers that mediate many functions in bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and protein secretion and that can act as nanowires carrying electric current. T4P are composed of a polymerized protein, pilin, and their assembly apparatuses share protein homologs with type II secretion systems in eubacteria and the flagella of archaea. T4P are found throughout Gram-negative bacterial families and have been studied most extensively in certain model Gram-negative species. Recently, it was discovered that T4P systems are also widespread among Gram-positive species, in particular the clostridia. Since Gram-positive and Gram-negative bacteria have many differences in cell wall architecture and other features, it is remarkable how similar the T4P core proteins are between these organisms, yet there are many key and interesting differences to be found as well. In this review, we compare the two T4P systems and identify and discuss the features they have in common and where they differ to provide a very broad-based view of T4P systems across all eubacterial species.

Indexed as

Bacterial ProteinsFimbriae, BacterialGram-Negative BacteriaGram-Positive BacteriaModels, BiologicalBacterial Proteins

Identifiers

PMID24006467
PMCPMC3811610
OpenAlexW2100429002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.