ReviewPediatric nephrology (Berlin, Germany)2014
Kidney regeneration: common themes from the embryo to the adult.
Review in Pediatric nephrology (Berlin, Germany), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- (Zebra)fishing for nephrogenesis genes.Tissue barriers · 2024Review
- Targeting the epidermal growth factor receptor (EGFR/ErbB) for the potential treatment of renal pathologies.Frontiers in pharmacology · 2024Review
- Kidney repair and regeneration: perspectives of the NIDDK (Re)Building a Kidney consortium.Kidney international · 2022Article
- Wnt signaling mediates new nephron formation during zebrafish kidney regeneration.Development (Cambridge, England) · 2019Article
- Enhancing regeneration after acute kidney injury by promoting cellular dedifferentiation in zebrafish.Disease models & mechanisms · 2019Article
- The role of macrophages during acute kidney injury: destruction and repair.Pediatric nephrology (Berlin, Germany) · 2019Review
- Acellular Mouse Kidney ECM can be Used as a Three-Dimensional Substrate to Test the Differentiation Potential of Embryonic Stem Cell Derived Renal Progenitors.Stem cell reviews and reports · 2017Article
- GDF11 improves tubular regeneration after acute kidney injury in elderly mice.Scientific reports · 2016Article
- Involvement of the Hippo pathway in regeneration and fibrogenesis after ischaemic acute kidney injury: YAP is the key effector.Clinical science (London, England : 1979) · 2016Article
- Kidney Regeneration in Adult Zebrafish by Gentamicin Induced Injury.Journal of visualized experiments : JoVE · 2015Article
- Fetal kidney stem cells ameliorate cisplatin induced acute renal failure and promote renal angiogenesis.World journal of stem cells · 2015Article
- Kidney Regeneration: Lessons from Development.Current pathobiology reports · 2015Article
- Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk.Stem cell reports · 2014Article
- Molecular imaging of urogenital diseases.Seminars in nuclear medicine · 2014Review
- Roles of Iroquois Transcription Factors in Kidney Development.Cell & developmental biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The vertebrate kidney has an inherent ability to regenerate following acute damage. Successful regeneration of the injured kidney requires the rapid replacement of damaged tubular epithelial cells and reconstitution of normal tubular function. Identifying the cells that participate in the regeneration process as well as the molecular mechanisms involved may reveal therapeutic targets for the treatment of kidney disease. Renal regeneration is associated with the expression of genetic pathways that are necessary for kidney organogenesis, suggesting that the regenerating tubular epithelium may be "reprogrammed" to a less-differentiated, progenitor state. This review will highlight data from various vertebrate models supporting the hypothesis that nephrogenic genes are reactivated as part of the process of kidney regeneration following acute kidney injury (AKI). Emphasis will be placed on the reactivation of developmental pathways and how our understanding of the resulting regeneration process may be enhanced by lessons learned in the embryonic kidney.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.