SynthesisHypertension research : official journal of the Japanese Society of Hypertension2013
The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies.
Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 175 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Clinical Investigation of the Effects of Acu-TENS and Acupressure on the Sleep Quality of Older Adults With Insomnia: A Pilot Randomized, Placebo-controlled Clinical Trial
Effect of a Novel Formulation on Sleep Parameters Among People With Poor Sleep Quality: A Randomized Controlled Trial
Who cites it
175 citing papers in PubMed, 7 syntheses or guidelines pooled it, 365 citations in OpenAlex.
- Association between sleep duration and hypertension incidence: Systematic review and meta-analysis of cohort studies.PloS one · 2024Pooled it
- Sleep Duration/Quality With Health Outcomes: An Umbrella Review of Meta-Analyses of Prospective Studies.Frontiers in medicine · 2021Pooled it
- Prevalence of Insomnia (Symptoms) in T2D and Association With Metabolic Parameters and Glycemic Control: Meta-Analysis.The Journal of clinical endocrinology and metabolism · 2020Pooled it
- Correlation between sleep duration and hypertension: a dose-response meta-analysis.Journal of human hypertension · 2019Pooled it
- Self-Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose-Response Meta-Analysis.Journal of the American Heart Association · 2018Pooled it
- Effectiveness and safety of moxibustion for primary insomnia: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2016Pooled it
- Auricular acupuncture with seed or pellet attachments for primary insomnia: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2015Pooled it
- Trial
- Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial.Journal of clinical hypertension (Greenwich, Conn.) · 2024Trial
- Does total sleep time substantially increase after cognitive behavioral therapy for insomnia?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Effect of suvorexant on nighttime blood pressure in hypertensive patients with insomnia: The SUPER-1 study.Journal of clinical hypertension (Greenwich, Conn.) · 2019Trial
- A behavioral intervention for insomnia improves blood pressure.Sleep medicine · 2017Trial
- Sleep duration and risk of stroke mortality among Chinese adults: Singapore Chinese health study.Stroke · 2014Trial
- Effects of bedtime melatonin treatment on blood pressure and arterial stiffness: a three-month, randomized, placebo-controlled crossover study in individuals with type 2 diabetes mellitus.Acta diabetologica · 2026Article
- Association between weekend catch-up sleep and stroke among US adults: A cross-sectional analysis of NHANES.Medicine · 2026Article
- Article
- Gender differences in sleep quality and its associated factors in patients with hypertension: a cross-sectional study.BMC public health · 2026Article
- Mechanisms Linking Insomnia and Cardiometabolic Disease Risk.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Insomnia and Hypertension: Importance of Objective Phenotyping and Comorbidity with Sleep Apnea.Current hypertension reports · 2026Review
- Sleep duration may not have any effect on the risk of stroke: insights from Mendelian randomization and prospective cohort studies.Archives of medical science : AMS · 2026Article
115 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess whether habitual sleep duration or insomnia increase the incidence of hypertension. PubMed, EMBASE and Cochrane were searched without language restriction. Prospective cohort studies of adults with at least a 1-year follow-up duration were included. Habitual sleep duration or symptoms of insomnia were assessed as baseline exposure, and the outcome was incidence of hypertension. Subgroup, meta-regression and sensitivity analyses were conducted to assess heterogeneity, and Egger's test was used to assess publication bias. Eleven studies (17 cohorts) were included. Short sleep duration, sleep continuity disturbance (SCD), early-morning awakening (EMA) and combined symptoms of insomnia increased the risk of hypertension incidence (the relative risks (95% confidence intervals) were 1.21 (1.05-1.40) for short sleep duration, 1.20 (1.06-1.36) for SCD, 1.14 (1.07-1.20) for EMA and 1.05 (1.01-1.08) for combined insomnia symptoms). Less evidence exists to support conclusions about the association between long sleep duration or difficulty falling asleep (DFA) and hypertension incidence. No obvious heterogeneity or publication biases were found. Our meta-analysis demonstrates that short sleep duration and single/combined symptoms of insomnia (except DFA) are associated with an increased risk of hypertension incidence. It is important to consider sleep duration and insomnia during hypertension prevention and treatment. More laboratory studies on potential mechanisms and prospective observational studies with objective measures of sleep are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.