ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2013
PRIMO: a graphical environment for the Monte Carlo simulation of Varian and Elekta linacs.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Assessment of dose distribution in pancreatic SABR in the presence of a metallic biliary stent using Monte Carlo modeling.Journal of applied clinical medical physics · 2026Article
- Validation of an in vivo transit dosimetry algorithm using Monte Carlo simulations and ionization chamber measurements.Journal of applied clinical medical physics · 2024Article
- Monte Carlo simulation of the Varian TrueBeam flattened-filtered beams using a surrogate geometry in PRIMO.Radiation oncology (London, England) · 2024Article
- Solution-Grown MAPbBrNanomaterials (Basel, Switzerland) · 2023Article
- Using PRIMO to determine the initial beam parameters of Elekta Synergy linac for electron beam energies of 6, 9, 12, and 15 MeV.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Article
- PRIMO Monte Carlo software as a tool for commissioning of an external beam radiotherapy treatment planning system.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023Article
- Complete patient exposure during paediatric brain cancer treatment for photon and proton therapy techniques including imaging procedures.Frontiers in oncology · 2023Article
- Monte Carlo simulation of linac using PRIMO.Radiation oncology (London, England) · 2022Article
- Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code.Journal of biomedical physics & engineering · 2022Article
- A feasibility study for in vivo treatment verification of IMRT using Monte Carlo dose calculation and deep learning-based modelling of EPID detector response.Radiation oncology (London, England) · 2022Article
- Comparison of PRIMO Monte Carlo code and Eclipse treatment planning system in calculation of dosimetric parameters in brain cancer radiotherapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Article
- Validation of virtual water phantom software for pre-treatment verification of single-isocenter multiple-target stereotactic radiosurgery.Journal of applied clinical medical physics · 2021Article
- Linac photon beam fine-tuning in PRIMO using the gamma-index analysis toolkit.Radiation oncology (London, England) · 2020Article
- MLC parameters from static fields to VMAT plans: an evaluation in a RT-dedicated MC environment (PRIMO).Radiation oncology (London, England) · 2019Article
- Treatment verification using Varian's dynalog files in the Monte Carlo system PRIMO.Radiation oncology (London, England) · 2019Article
- PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators.Radiation oncology (London, England) · 2019Article
- DPM as a radiation transport engine for PRIMO.Radiation oncology (London, England) · 2018Article
- PRIMO Monte Carlo software benchmarked against a reference dosimetry dataset for 6 MV photon beams from Varian linacs.Radiation oncology (London, England) · 2018Article
- Collimator scatter factor: Monte Carlo and in-air measurements approaches.Radiation oncology (London, England) · 2018Article
- Monte Carlo simulations in radiotherapy dosimetry.Radiation oncology (London, England) · 2018Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe accurate Monte Carlo simulation of a linac requires a detailed description of its geometry and the application of elaborate variance-reduction techniques for radiation transport. Both tasks entail a substantial coding effort and demand advanced knowledge of the intricacies of the Monte Carlo system being used.
methodsPRIMO, a new Monte Carlo system that allows the effortless simulation of most Varian and Elekta linacs, including their multileaf collimators and electron applicators, is introduced. PRIMO combines (1) accurate physics from the PENELOPE code, (2) dedicated variance-reduction techniques that significantly reduce the computation time, and (3) a user-friendly graphical interface with tools for the analysis of the generated data. PRIMO can tally dose distributions in phantoms and computerized tomographies, handle phase-space files in IAEA format, and import structures (planning target volumes, organs at risk) in the DICOM RT-STRUCT standard.
resultsA prostate treatment, conformed with a high definition Millenium multileaf collimator (MLC 120HD) from a Varian Clinac 2100 C/D, is presented as an example. The computation of the dose distribution in 1.86×3.00×1.86 mm3 voxels with an average 2% standard statistical uncertainty, performed on an eight-core Intel Xeon at 2.67 GHz, took 1.8 h-excluding the patient-independent part of the linac, which required 3.8 h but it is simulated only once.
conclusionPRIMO is a self-contained user-friendly system that facilitates the Monte Carlo simulation of dose distributions produced by most currently available linacs. This opens the door for routine use of Monte Carlo in clinical research and quality assurance purposes. It is free software that can be downloaded from http://www.primoproject.net.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.