ArticleDiagnostic and interventional radiology (Ankara, Turkey)
Transjugular intrahepatic portosystemic shunt for the treatment of medically refractory ascites.
Article in Diagnostic and interventional radiology (Ankara, Turkey). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Transjugular Intrahepatic Portosystemic Shunt Creation for Treatment of Gastric Varices: Systematic Literature Review and Meta-Analysis of Clinical Outcomes.Cardiovascular and interventional radiology · 2021Pooled it
- Guideline
- Optimal threshold of portal pressure gradient for patients with ascites after covered TIPS: a multicentre cohort study.Hepatology international · 2025Article
- Determining the optimal portal pressure gradient after small-diameter TIPS for ascites: a retrospective study.Therapeutic advances in gastroenterology · 2025Article
- The Role of Transjugular Intrahepatic Portosystemic Shunt for the Management of Ascites in Patients with Decompensated Cirrhosis.Journal of clinical medicine · 2024Review
- Transjugular Intrahepatic Portosystemic Shunt: Devices Evolution, Technical Tips and Future Perspectives.Journal of clinical medicine · 2023Review
- Change in Platelet Count after Transjugular Intrahepatic Portosystemic Shunt Creation: An Advancing Liver Therapeutic Approaches (ALTA) Group Study.Journal of vascular and interventional radiology : JVIR · 2023Article
- Interventional recanalization therapy in patients with non-cirrhotic, non-malignant portal vein thrombosis: comparison between transjugular versus transhepatic access.Abdominal radiology (New York) · 2022Article
- High Incidence of Hepatic Encephalopathy After Viatorr Controlled Expansion Transjugular Intrahepatic Portosystemic Shunt Creation.Digestive diseases and sciences · 2021Article
- Retrospective Study of Transjugular Intrahepatic Portosystemic Shunt Placement for Cirrhotic Portal Hypertension.GE Portuguese journal of gastroenterology · 2020Article
- Evaluation and Management of Cirrhotic Patients Undergoing Elective Surgery.Current gastroenterology reports · 2019Review
- Transjugular Intrahepatic Portosystemic Shunt Dysfunction: Concordance of Clinical Findings, Doppler Ultrasound Examination, and Shunt Venography.Journal of clinical imaging science · 2016Article
- Retrograde puncture assisted hepatic vein recanalization in treating Budd-Chiari syndrome with segmental obstruction of hepatic vein.La Radiologia medica · 2015Article
- Parallel transjugular intrahepatic portosystemic shunt for controlling portal hypertension complications in cirrhotic patients.World journal of gastroenterology · 2014Article
- Percutaneous Portosystemic Shunts: TIPS and Beyond.Seminars in interventional radiology · 2014Review
- How quickly does ascites respond to TIPS? Clinical follow-up of a cohort of eighty patients.Diagnostic and interventional radiology (Ankara, Turkey)Article
- Accessory hepatic vein recanalization for treatment of Budd-Chiari syndrome due to long-segment obstruction of the hepatic vein: initial clinical experience.Diagnostic and interventional radiology (Ankara, Turkey)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was performed to assess the safety, efficacy, and clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) creation for treatment of medically refractory ascites and to identify prognostic factors for clinical response, morbidity, and mortality. MATERIALS AND
methodsIn this retrospective study, 80 patients (male:female, 52:28; mean age, 56 years; mean Model for End-Stage Liver Disease [MELD] score, 15.1) who underwent elective TIPS creation for refractory ascites between 1999-2012 were studied. A medical record review was performed to identify data on demographics, liver disease, procedures, and outcome. The influence of these parameters on 30-day, 90-day, and one-year mortality was assessed using binary logistic regression. Overall survival was analyzed with Kaplan-Meier statistics.
resultsTIPS was successfully created using covered (n=70) or bare metal (n=10) stents. Hemodynamic success was achieved in all cases. The mean final portosystemic pressure gradient (PSG) was 6.8 mmHg. Thirty-day complications included mild encephalopathy in 35% of patients. Clinical improvement in ascites occurred in 78% of patients, with complete resolution or a ≥50% decrease in 66% of patients. No predictors of response or optimal PSG threshold were identified. The 30-day, 90-day, and one-year mortality rates were 14%, 23%, and 33%, respectively. Patient age (P = 0.026) was associated with 30-day mortality, while final PSG was associated with 90-day (P = 0.020) and one year (P = 0.032) mortality. No predictors of overall survival were identified.
conclusionTIPS creation effectively treats medically refractory ascites with nearly 80% efficacy. The incidence of mild encephalopathy is nontrivial. Older age and final PSG are associated with mortality, and these factors should be considered in patient selection and procedure performance.
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