Evidence map›Paper›PMID 24004508›Full record

ReviewEnvironmental health : a global access science source2013

Arsenic immunotoxicity: a review.

Nygerma L Dangleben, Christine F Skibola, Martyn T Smith

Open access · goldAbstract readReview
In one paragraph

Review in Environmental health : a global access science source, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
21.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 1 synthesis or guideline pooled it, 272 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Arsenome, Arsenobolome, and Arsenobiolome.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Guardians under Siege: Exploring Pollution's Effects on Human Immunity.International journal of molecular sciences · 2024
    Review
  14. Review
  15. Heavy metals, oxidative stress, and the role of AhR signaling.Toxicology and applied pharmacology · 2024
    Review
  16. Article
  17. Investigation of The Effect of Metal-based MedicineEndocrine, metabolic & immune disorders drug targets · 2024
    Article
  18. Article
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nygerma L DanglebenDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720, USA. martynts@berkeley.edu.
Christine F Skibola
Martyn T Smith
University of California, Berkeley · USUniversity of Alabama at Birmingham · US

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MORELLO-FROSCH, RACHEL ADELE · 1987 to 2025
$74.6M
NIEHS NIH HHS P42 ES004705
6 · The paper itself

Abstract

Exposure to arsenic (As) is a global public health problem because of its association with various cancers and numerous other pathological effects, and millions of people worldwide are exposed to As on a regular basis. Increasing lines of evidence indicate that As may adversely affect the immune system, but its specific effects on immune function are poorly understood. Therefore, we conducted a literature search of non-cancer immune-related effects associated with As exposure and summarized the known immunotoxicological effects of As in humans, animals and in vitro models. Overall, the data show that chronic exposure to As has the potential to impair vital immune responses which could lead to increased risk of infections and chronic diseases, including various cancers. Although animal and in vitro models provide some insight into potential mechanisms of the As-related immunotoxicity observed in human populations, further investigation, particularly in humans, is needed to better understand the relationship between As exposure and the development of disease.

Indexed as

Environmental ExposureAnimalsArsenicArsenic PoisoningEnvironmental MonitoringEnvironmental PollutantsHumansArsenicEnvironmental Pollutants

Identifiers

PMID24004508
PMCPMC3848751
OpenAlexW2126757193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.