Evidence map›Paper›PMID 24004404›Full record

ReviewTissue engineering. Part B, Reviews2014

Endothelial outgrowth cells: function and performance in vascular grafts.

Jeremy J Glynn, Monica T Hinds

Open access · greenAbstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Bioengineered · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Challenges and Possibilities of Cell-Based Tissue-Engineered Vascular Grafts.Cyborg and bionic systems (Washington, D.C.) · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Historical Perspective and Future Direction of Blood Vessel Developments.Cold Spring Harbor perspectives in medicine · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeremy J GlynnDepartment of Biomedical Engineering, Oregon Health & Science University , Portland, Oregon.
Monica T Hinds
Oregon Health & Science University · US

Funding

Vascular tissue engineering: rational design using modelingR01HL095474 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T · 2009 to 2012
$2.4M
Modified surfaces to capture endothelial progenitor cells for venous applicationsR01HL103728 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T · 2010 to 2014
$1.9M
NHLBI NIH HHS R01 HL095474NHLBI NIH HHS R01HL095474NHLBI NIH HHS R01 HL103728NHLBI NIH HHS R01HL103728
6 · The paper itself

Abstract

The clinical need for vascular grafts continues to grow. Tissue engineering strategies have been employed to develop vascular grafts for patients lacking sufficient autologous vessels for grafting. Restoring a functional endothelium on the graft lumen has been shown to greatly improve the long-term patency of small-diameter grafts. However, obtaining an autologous source of endothelial cells for in vitro endothelialization is invasive and often not a viable option. Endothelial outgrowth cells (EOCs), derived from circulating progenitor cells in peripheral blood, provide an alternative cell source for engineering an autologous endothelium. This review aims at highlighting the role of EOCs in the regulation of processes that are central to vascular graft performance. To characterize EOC performance in vascular grafts, this review identifies the characteristics of EOCs, defines functional performance criteria for EOCs in vascular grafts, and summarizes the existing work in developing vascular grafts with EOCs.

Indexed as

BioprosthesisBlood Vessel ProsthesisAnimalsEndothelial CellsHumansStem CellsTissue Engineering

Identifiers

PMID24004404
PMCPMC4123462
OpenAlexW2334740759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.