Evidence map›Paper›PMID 24003385›Full record

ArticleAllergy, asthma & immunology research2013

The effect of vitamin d status on pediatric asthma at a university hospital, Thailand.

Wijittra Krobtrakulchai, Jittima Praikanahok, Nualanong Visitsunthorn, Pakit Vichyanond, Kotchamol Manonukul, Busadee Pratumvinit, Orathai Jirapongsananuruk

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Allergy, asthma & immunology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01432678 (Vitamin D Status in Pediatric Asthma), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01432678 completednot on this map

Vitamin D Status in Pediatric Asthma

TypeobservationalSponsorMahidol UniversityRan2011 to 2013Enrolled120ConditionsVitamin D Deficiency
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Micronutrients and the Risk of Allergic Diseases in School Children.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Vitamin d levels in children with bronchial asthma.Journal of clinical and diagnostic research : JCDR · 2014
    Article
  11. Vitamin D in inflammatory diseases.Frontiers in physiology · 2014
    Review
  12. Article
  13. Review
  14. Article
  15. The Role of Vitamin D in Pediatric Asthma.Annals of pediatrics & child health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wijittra KrobtrakulchaiDepartment of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Jittima Praikanahok
Nualanong Visitsunthorn
Pakit Vichyanond
Kotchamol Manonukul
Busadee Pratumvinit
Orathai Jirapongsananuruk
Siriraj Hospital · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn the USA and Europe, hypovitaminosis D is associated with increased asthma severity, emergency department (ED) visit, and impaired pulmonary function in asthmatic patients. However, in tropical countries, data on the effect of vitamin D status on asthma is limited. This study evaluates the relationship between vitamin D status and the level of asthma control as well as other asthmatic parameters.

methodsAsthmatic children were evaluated for serum 25-hydroxyvitamin D, pulmonary function tests, a skin prick test, and the level of asthma control.

resultsA total of 125 asthmatic children were recruited (boys, 66.4%). Their mean age±SD was 10.8±3.0 years. Vitamin D statuses were: deficiency (<20 ng/mL) in 19.2% of the patients, insufficiency (20-30 ng/mL) in 44.8%, and sufficiency (>30 ng/mL) in 36%. The vitamin D levels were 25.9±9.4 ng/mL in uncontrolled patients, 29.2±8.6 ng/mL in partly controlled patients, and 27.9±8.0 ng/mL in controlled patients (P>0.05). There were no significant differences in pulmonary function, asthma exacerbation, inhaled-corticosteroid (ICS) dose, anti-inflammatory drugs, or ED visit or hospitalization between different vitamin D statuses. Vitamin D deficiency patients were older and had a delayed onset of asthma than insufficiency or sufficiency patients. There was no significant correlation between serum vitamin D and pulmonary function/doses of ICS.

conclusionsHigh prevalences of vitamin D deficiency and insufficiency were found in asthmatic children in Thailand; however, there was no significant relationship between vitamin D status and the level of asthma control or other asthma parameters.

Indexed as

25-hydroxyvitamin DAsthmachildrencorticosteroidvitamin D

Identifiers

PMID24003385
PMCPMC3756175
OpenAlexW1991371918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.