ReviewAllergy, asthma & immunology research2013
Unraveling the genetic basis of aspirin hypersensitivity in asthma beyond arachidonate pathways.
Review in Allergy, asthma & immunology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Transfluthrin is Associated with High Susceptibility to Asthma in Children with Promoter Variants of Beta Chain of High-Affinity Receptor IgE and Tumour Necrosis Factors-α Genes.Biochemical genetics · 2024Article
- Review
- Polymorphisms in HumanGenes · 2022Article
- Article
- Epigenetic Changes in Asthma: Role of DNA CpG Methylation.Tuberculosis and respiratory diseases · 2020Review
- Complementary Participation of Genetics and Epigenetics in Development of NSAID-exacerbated Respiratory Disease.Allergy, asthma & immunology research · 2019Review
- Lessons Learned From GWAS of Asthma.Allergy, asthma & immunology research · 2019Review
- Clinical Implications of Single Nucleotide Polymorphisms in Diagnosis of Asthma and its Subtypes.Yonsei medical journal · 2019Review
- Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American population.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Article
- Drug Hypersensitivity.Deutsches Arzteblatt international · 2018Review
- Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma.BMC genomics · 2017Article
- Self-report prevalence and associated factors to drug hypersensitivity in Mexican young adults.Asia Pacific allergy · 2017Article
- Aspirin-Exacerbated Respiratory Disease as an Endotype of Chronic Rhinosinusitis.Immunology and allergy clinics of North America · 2016Review
- Pharmacogenetics and Predictive Testing of Drug Hypersensitivity Reactions.Frontiers in pharmacology · 2016Review
- Aspirin-Exacerbated Diseases: Advances in Asthma with Nasal Polyposis, Urticaria, Angioedema, and Anaphylaxis.Current allergy and asthma reports · 2015Review
- Progress and Prospect: A Bibliometric Analysis of Research Papers by Korean Allergists Over Recent Five Years (2009-2013).Allergy, asthma & immunology research · 2015Article
- Development of a genetic marker set to diagnose aspirin-exacerbated respiratory disease in a genome-wide association study.The pharmacogenomics journal · 2015Article
- Hypersensitivity to Aspirin and other NSAIDs: Diagnostic Approach in Patients with Chronic Rhinosinusitis.Current allergy and asthma reports · 2015Review
- Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects.Yonsei medical journal · 2015Review
- Seven steps to the diagnosis of NSAIDs hypersensitivity: how to apply a new classification in real practice?Allergy, asthma & immunology research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although aspirin-exacerbated respiratory disease (AERD) has attracted a great deal of attention because of its association with severe asthma, it remains widely under-diagnosed in the asthmatic population. Oral aspirin challenge is the best method of diagnosing AERD, but this is a time-consuming procedure with serious complications in some cases. Thus, development of non-invasive methods for easy diagnosis is necessary to prevent unexpected complications of aspirin use in susceptible patients. For the past decade, many studies have attempted to elucidate the genetic variants responsible for risk of AERD. Several approaches have been applied in these genetic studies. To date, a limited number of biologically plausible candidate genes in the arachidonate and immune and inflammatory pathways have been studied. Recently, a genome-wide association study was performed. In this review, the results of these studies are summarized, and their limitations discussed. In addition to the genetic variants, changes in methylation patterns on CpG sites have recently been identified in a target tissue of aspirin hypersensitivity. Finally, perspectives on application of new genomic technologies are introduced; these will aid our understanding of the genetic pathogenesis of aspirin hypersensitivity in asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.