SynthesisRheumatology (Oxford, England)2013
The prevalence of depression in rheumatoid arthritis: a systematic review and meta-analysis.
Synthesis in Rheumatology (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06068920 (Evaluation of Distress and Related Factors in Patients With Rheumatoid Arthritis), which is not on this map. Cited by 408 papers, 13 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Distress and Related Factors in Patients With Rheumatoid Arthritis
Who cites it
408 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Pooled it
- The Economic Burden of Inflammatory Arthritis: A Systematic Review.PharmacoEconomics · 2025Pooled it
- Pooled it
- Effects of exercise on depression in patients with rheumatic diseases: a systematic review and meta-analysis.Zeitschrift fur Rheumatologie · 2024Pooled it
- The Depression Prevalence in Chinese Patients with Rheumatoid Arthritis: A Systematic Review and Meta-analysis.Actas espanolas de psiquiatria · 2023Pooled it
- Patient self-reported instruments for assessing symptoms in rheumatoid arthritis.Rheumatology international · 2023Pooled it
- Prevalence of developmental dysplasia of the hip (DDH) in infants: a systematic review and meta-analysis.BMJ paediatrics open · 2023Pooled it
- Nursing interventions for patients with rheumatic and musculoskeletal diseases on biological therapies: a systematic literature review.Clinical rheumatology · 2023Pooled it
- Global prevalence and trend of anxiety among graduate students: A systematic review and meta-analysis.Brain and behavior · 2023Pooled it
- Assessment of bidirectional relationships between depression and rheumatoid arthritis among adults: a two-sample Mendelian randomization study.Clinical rheumatology · 2023Pooled it
- Results from a living systematic review of the prevalence of mood and anxiety disorders and factors associated with symptoms in systemic sclerosis.Scientific reports · 2023Pooled it
- Interventions for Depressive Symptoms in People Living with Chronic Pain: A Systematic Review of Meta-Analyses.Pain medicine (Malden, Mass.) · 2022Pooled it
- Association between social deprivation and disease activity in rheumatoid arthritis: a systematic literature review.RMD open · 2022Pooled it
- [Delegation of medical duties to qualified rheumatology assistants : Effect on depression and anxiety in patients with rheumatoid arthritis].Zeitschrift fur Rheumatologie · 2024Trial
- Impacts of socioeconomic status on ambulatory care sensitive condition hospitalizations in RA.Rheumatology (Oxford, England) · 2026Article
- Psychological Distress, Somatic Symptom Burden, and Quality of Life in Rheumatoid Arthritis: A Cross-Sectional Study in Bosnia and Herzegovina.Healthcare (Basel, Switzerland) · 2026Article
- Global population-level concurrence and directional associations between rheumatoid arthritis and depressive disorders: an SDI-stratified time-series analysis using GBD 2021.Clinical rheumatology · 2026Article
- The Treatment-Related Burnout Scale for Rheumatic Diseases: Development and Preliminary Validation.Clinical rheumatology · 2026Article
- Risk of misclassification of rheumatoid arthritis activity in patients with depression: a prospective ultrasound study.Clinical rheumatology · 2026Article
- Comparative Effects of Sertraline, Methotrexate, and Biologic Therapies on Circulating Inflammatory and Neurotrophic Mediators and Striatal Gene Expression in Collagen-Induced Arthritis.International journal of molecular sciences · 2026Article
348 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere is substantial uncertainty regarding the prevalence of depression in RA. We conducted a systematic review aiming to describe the prevalence of depression in RA.
methodsWeb of Science, PsycINFO, CINAHL, Embase, Medline and PubMed were searched for cross-sectional studies reporting a prevalence estimate for depression in adult RA patients. Studies were reviewed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and a meta-analysis was performed.
resultsA total of 72 studies, including 13,189 patients, were eligible for inclusion in the review. Forty-three methods of defining depression were reported. Meta-analyses revealed the prevalence of major depressive disorder to be 16.8% (95% CI 10%, 24%). According to the PHQ-9, the prevalence of depression was 38.8% (95% CI 34%, 43%), and prevalence levels according to the HADS with thresholds of 8 and 11 were 34.2% (95% CI 25%, 44%) and 14.8% (95% CI 12%, 18%), respectively. The main influence on depression prevalence was the mean age of the sample.
conclusionDepression is highly prevalent in RA and associated with poorer RA outcomes. This suggests that optimal care of RA patients may include the detection and management of depression.
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