Evidence map›Paper›PMID 24002589›Full record

ArticleBritish journal of cancer2013

Exogenous hormone use, reproductive history and risk of adult myeloid leukaemia.

J N Poynter, R Fonstad, C K Blair, M Roesler, J R Cerhan, B Hirsch, P Nguyen, J A Ross

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Hormonal and Reproductive Factors and Risk of Myeloproliferative Neoplasms in Postmenopausal Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

J N Poynter1] Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, MMC715, 420 Delaware Street S.E., Minneapolis, MN 55455, USA [2] Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
R Fonstad
C K Blair
M Roesler
J R Cerhan
B Hirsch
P Nguyen
J A Ross
University of Minnesota · USUniversity of Minnesota Medical Center · USMayo Clinic in Arizona · USMayo Clinic in Florida · USUniversity of Alabama at Birmingham · US

Funding

Cancer Prevention & Control Training ProgramR25CA047888 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DEMARK-WAHNEFRIED, WENDY, MENESES, KAREN M · 1988 to 2016
$11.2M
Predictors of Adult LeukemiaR01CA107143 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI ROSS, JULIE ANN · 2005 to 2009
$2.5M
Established Investigator Award in Pediatric Cancer EpidemiologyK05CA157439 · NCI · UNIVERSITY OF MINNESOTA · PI ROSS, JULIE ANN · 2011 to 2015
$695k
NCI NIH HHS K05 CA157439NCI NIH HHS R01 CA107143NCI NIH HHS R25 CA047888
6 · The paper itself

Abstract

backgroundA hormonal aetiology is one explanation for the lower incidence of myeloid leukaemia in women compared with men.

methodsIn this population-based case-control study, we evaluated associations between exogenous hormone use and reproductive history and myeloid leukaemia, overall and by disease subtype.

resultsWe observed a suggestive association between oral contraceptive use and acute myeloid leukaemia (odds ratio=0.55, 95% confidence interval=0.32-0.96). Hormone replacement therapy and reproductive factors were not associated with risk.

conclusionDespite the biological plausibility for a role of oestrogen in leukaemogenesis, other aetiologic factors are likely to explain the differing incidence rates in males and females.

Indexed as

Hormone Replacement TherapyReproductive HistoryAdultAgedCase-Control StudiesContraceptives, OralEstrogensFemaleHumansLeukemia, MyeloidMaleMiddle AgedRiskRisk FactorsYoung AdultContraceptives, OralEstrogens

Identifiers

PMID24002589
PMCPMC3790163
OpenAlexW2029328137

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.