Evidence map›Paper›PMID 24002141›Full record

ArticleMolecules (Basel, Switzerland)2013

Effect of non-pharmacologic vitamin D status correction on circulating bone markers in healthy overweight and obese Saudis.

Nasser M Al-Daghri, Khalid M Alkharfy, Abdulaziz Al-Othman, Sobhy M Yakout, Yousef Al-Saleh, Mona Fouda, Shaun Sabico

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nasser M Al-DaghriBiomarkers Research Program, Department of Biochemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia. aldaghri2011@gmail.com
Khalid M Alkharfy
Abdulaziz Al-Othman
Sobhy M Yakout
Yousef Al-Saleh
Mona Fouda
Shaun Sabico
King Saud University · SAKing Khalid University Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While moderate to severe vitamin D deficiency is prevalent in Saudi Arabia, skeletal effects associated with this deficiency are not common in this population. In this interventional study we measured the effects of improving vitamin D status on bone biochemical markers in overweight and obese adult Saudis. A total of 47 volunteers (21 males, 26 females) out of the initial 95 subjects were given verbal advice to expose themselves to sunlight for 5-30 min twice weekly and were encouraged to increase their intake of vitamin D-rich foods. Serum 25(OH)D, osteocalcin, and type 1 collagen cross-linked C-telopeptide (CTx), were measured at baseline and after one year. A significant decrease in the prevalence of vitamin D deficiency was observed (44% to 27%) after one year follow-up (p = 0.025). Also, a parallel significant increase in osteocalcin and a decrease in CTX and osteoprotegerin were observed. The results suggest that a modest increase in vitamin D levels among overweight and obese subjects through the promotion of lifestyle changes for one year have marginal effects in bone turnover markers as well as obesity itself.

Indexed as

AdultBiomarkersCollagen Type IDietFemaleHumansMaleMiddle AgedObesityOsteocalcinOverweightPeptidesPrevalenceSaudi ArabiaSunlightVitamin DBiomarkersCollagen Type Icollagen type I trimeric cross-linked peptideOsteocalcinPeptidesVitamin D

Identifiers

PMID24002141
PMCPMC6269801
OpenAlexW2004524977

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.