Evidence map›Paper›PMID 24002039›Full record

ArticleEuropean journal of clinical nutrition2013

Maternal and infant vitamin D status during the first 9 months of infant life-a cohort study.

S Við Streym, U Kristine Moller, L Rejnmark, L Heickendorff, L Mosekilde, P Vestergaard

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02548520 (Vitamin D Status in the First 9 Months of Life), which is not on this map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02548520 completednot on this map

Vitamin D Status in the First 9 Months of Life

TypeobservationalSponsorUniversity of AarhusRan2008 to 2012Enrolled107ConditionsRickets, Osteomalacia, OsteoporosisArmsBlood and breastmilk samples
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effect of Oral Vitamin D3 Supplementation in Exclusively Breastfed Newborns: Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S Við StreymDepartment of Endocrinology and Internal Medicine (MEA), Aarhus University Hospital, Aarhus, Denmark.
U Kristine Moller
L Rejnmark
L Heickendorff
L Mosekilde
P Vestergaard

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe objective of this study was to assess vitamin D status and possible consequences of low plasma 25-hydroxyvitamin D (25OHD) levels in a population of healthy mothers and their infants. SUBJECTS/

methodsA total of 107 women aged 24-41 years gave birth to 108 infants. They were followed up three times during 9 months.

resultsCord blood 25OHD level (43.3 ± 20.4  nmol/l) on average was 62 ± 16% of maternal levels (73.3 ± 30.7  nmol/l), measured 1-2 weeks postpartum. Cord blood 25OHD correlated positively with maternal 25OHD levels (r=0.83, P<0.001). At birth, 23% of mothers and 61% of infants had 25OHD <50  nmol/l. Vitamin D deficiency (25OHD<25  nmol/l) was present in 66% of the children born by mothers with 25OHD levels below 50  nmol/l (P<0.01), whereas only one child was born with deficiency among mothers with 25OHD >50  nmol/l. During follow-up, most of the children (>85%) had 25OHD levels >50  nmol/l, which most likely was attributable to the use of supplements, as more than 95% of the children were given daily vitamin D supplements of 10  μg of vitamin D.Cord blood parathyroid hormone levels were very low (median 0.21; interquartile range 0.11-0.33  pmol/l), with increasing levels (P<0.01) reaching 3.08 (2.67-3.92  pmol/l) at the last visit. Vitamin D levels were not associated with anthropometric indices of the newborn infant or their growth during follow-up.

conclusionsVitamin D deficiency is widespread in newborn. Maternal 25OHD levels above 50  nmol/l are needed to prevent vitamin D deficiency among newborn.

Indexed as

AdultCohort StudiesDietary SupplementsFemaleFetal BloodFollow-Up StudiesHumansInfantInfant, NewbornInfant, Newborn, DiseasesMaleMothersVitamin DVitamin D DeficiencyVitamin D

Identifiers

PMID24002039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.