ArticleJournal of immunological methods2013
BlockLogo: visualization of peptide and sequence motif conservation.
Article in Journal of immunological methods, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- DiMA: sequence diversity dynamics analyser for viruses.Briefings in bioinformatics · 2024Article
- plotnineSeqSuite: a Python package for visualizing sequence data using ggplot2 style.BMC genomics · 2023Article
- Cryptic association of B7-2 molecules and its implication for clustering.Protein science : a publication of the Protein Society · 2021Article
- Local adaptive evolution of two distinct clades of Beijing and T families of Mycobacterium tuberculosis in Chongqing: a Bayesian population structure and phylogenetic study.Infectious diseases of poverty · 2020Article
- Logomaker: beautiful sequence logos in Python.Bioinformatics (Oxford, England) · 2020Article
- Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver.Journal of lipid research · 2020Article
- ProteomicsBrowser: MS/proteomics data visualization and investigation.Bioinformatics (Oxford, England) · 2019Article
- Clonal analysis of Salmonella-specific effector T cells reveals serovar-specific and cross-reactive T cell responses.Nature immunology · 2018Article
- Epitope-Binding Characteristics for Risk versus Protective DRB1 Alleles for Visceral Leishmaniasis.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- New Mycobacterium tuberculosis Beijing clonal complexes in China revealed by phylogenetic and Bayesian population structure analyses of 24-loci MIRU-VNTRs.Scientific reports · 2017Article
- Article
- Shetti, a simple tool to parse, manipulate and search large datasets of sequences.Microbial genomics · 2015Article
- Intrinsic disorder mediates hepatitis C virus core-host cell protein interactions.Protein science : a publication of the Protein Society · 2015Article
- A systematic analysis of a broadly neutralizing antibody AR3C epitopes on Hepatitis C virus E2 envelope glycoprotein and their cross-reactivity.BMC medical genomics · 2015Article
- A computational method for identification of vaccine targets from protein regions of conserved human leukocyte antigen binding.BMC medical genomics · 2015Article
- FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses.Journal of immunology research · 2015Article
- Bioinformatics for cancer immunotherapy target discovery.Cancer immunology, immunotherapy : CII · 2014Review
- Big data analytics in immunology: a knowledge-based approach.BioMed research international · 2014Article
- Large-scale analysis of B-cell epitopes on influenza virus hemagglutinin - implications for cross-reactivity of neutralizing antibodies.Frontiers in immunology · 2014Article
- Genome-wide association study of IgG1 responses to the choline-binding protein PspC of Streptococcus pneumoniae.Genes and immunityArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
BlockLogo is a web-server application for the visualization of protein and nucleotide fragments, continuous protein sequence motifs, and discontinuous sequence motifs using calculation of block entropy from multiple sequence alignments. The user input consists of a multiple sequence alignment, selection of motif positions, type of sequence, and output format definition. The output has BlockLogo along with the sequence logo, and a table of motif frequencies. We deployed BlockLogo as an online application and have demonstrated its utility through examples that show visualization of T-cell epitopes and B-cell epitopes (both continuous and discontinuous). Our additional example shows a visualization and analysis of structural motifs that determine the specificity of peptide binding to HLA-DR molecules. The BlockLogo server also employs selected experimentally validated prediction algorithms to enable on-the-fly prediction of MHC binding affinity to 15 common HLA class I and class II alleles as well as visual analysis of discontinuous epitopes from multiple sequence alignments. It enables the visualization and analysis of structural and functional motifs that are usually described as regular expressions. It provides a compact view of discontinuous motifs composed of distant positions within biological sequences. BlockLogo is available at: http://research4.dfci.harvard.edu/cvc/blocklogo/ and http://met-hilab.bu.edu/blocklogo/.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.