Evidence map›Paper›PMID 24001391›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Hematological particularities and co-infections in injected drug users with AIDS.

Denise Menezes Brunetta, Gil Cunha De Santis, Fernando Crivelenti Vilar, Renata Amorim Brandão, Renata Zomer de Albernaz Muniz, Geovana Momo Nogueira de Lima, Manuela Emiliana Amorelli-Chacel, Dimas Tadeu Covas, Alcyone Artioli Machado

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Denise Menezes BrunettaCenter for Cell Based Therapy, Medical School of Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto, SP, Brazil. Electronic address: dbrunetta@hotmail.com.
Gil Cunha De Santis
Fernando Crivelenti Vilar
Renata Amorim Brandão
Renata Zomer de Albernaz Muniz
Geovana Momo Nogueira de Lima
Manuela Emiliana Amorelli-Chacel
Dimas Tadeu Covas
Alcyone Artioli Machado

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV patients infected through injected drug use have poorer prognosis than other groups. We evaluated the hematological alterations and rates of co-infections in injected drug use patients with AIDS. Injected drug use patients were younger, predominantly of male gender, and presented lower CD4, total lymphocyte, and platelet counts, but not neutrophil count, than control group. Injected drug use patients had a higher rate of hepatitis C and mycobacteria infection. Furthermore, all injected drug use patients with hemoglobin <10.0 g dL(-1) and lymphocyte <1000μL(-1) had CD4 count lower than 100μL(-1). In conclusion, HIV-infected injected drug use patients constitute a special group of patients, and hemoglobin concentration and lymphocyte count can be used as surrogate markers for disease severity.

Indexed as

Acquired Immunodeficiency SyndromeAdolescentAdultAgedCD4 Lymphocyte CountCoinfectionCross-Sectional StudiesDiagnosis, Dual (Psychiatry)Disease ProgressionFemaleHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexSubstance Abuse, IntravenousAIDSAnemiaHCVInjected drug useMycobacteria

Identifiers

PMID24001391
PMCPMC9427417

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.