ArticleCurrent eye research2013
Effect of contact lens on optical coherence tomography imaging of rodent retina.
Article in Current eye research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- A Novel Retinal Nerve Fiber Layer Biomarker of Amyotrophic Lateral Sclerosis (ALS) Identified Using Longitudinal in vivo Ocular Imaging.Eye and brain · 2025Article
- Immune Analysis Using Vitreous Optical Coherence Tomography Imaging in Rats with Steroid-Induced Glaucoma.Biomedicines · 2024Article
- Article
- RETRACTED: Preparation and Characterization of Poly(vinyl acetate-co-2-hydroxyethyl methacrylate) and In Vitro Application as Contact Lens for Acyclovir Delivery.International journal of molecular sciences · 2023Article
- Analysis of Parainflammation in Chronic Glaucoma Using Vitreous-OCT Imaging.Biomedicines · 2021Article
- Influence of Chronic Ocular Hypertension on Emmetropia: Refractive, Structural and Functional Study in Two Rat Models.Journal of clinical medicine · 2021Article
- Comparative Optical Coherence Tomography Angiography of Wild-Type and rd10 Mouse Retinas.Translational vision science & technology · 2018Article
- Effect of a contact lens on mouse retinal in vivo imaging: Effective focal length changes and monochromatic aberrations.Experimental eye research · 2018Article
- Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements.Journal of biomedical optics · 2017Article
- Fabricating customized hydrogel contact lens.Scientific reports · 2016Article
- In vivo optical coherence tomography of stimulus-evoked intrinsic optical signals in mouse retinas.Journal of biomedical optics · 2016Article
- Depth-resolved rhodopsin molecular contrast imaging for functional assessment of photoreceptors.Scientific reports · 2015Article
- In vivo imaging rhodopsin distribution in the photoreceptors with nano-second pulsed scanning laser ophthalmoscopy.Quantitative imaging in medicine and surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeTo evaluate the effect of powerless contact lens on improving the quality of optical coherence tomography imaging of rodent retina.
methodsA spectral-domain optical coherence tomography (SD-OCT) system was built for in vivo imaging of rodent retina. The calibrated depth resolution of the system was 3 µm in tissue. A commercial powerless contact lens for rat eye was tested in the experiments. For each rat eye, the retina was imaged in vivo sequentially first without wearing contact lens and then with wearing contact lens. The lateral resolution and signal-to-noise ratio of the OCT images with and without contact lens were compared to evaluate the improvement of image quality.
resultsThe fundus images generated from the measured 3D OCT datasets with contact lens showed sharper retinal blood vessels than those without contact lens. The contrast of the retinal blood vessels was also significantly enhanced in the OCT fundus images with contact lens. As high as 10 dB improvements in SNR was observed for OCT images with contact lens compared to the images of the same retinal area without contact lens.
conclusionsWe have demonstrated that the use of powerless contact lens on rat eye can significantly improve OCT image quality of rodent retina, which is a benefit in addition to preventing cataract formation. We believe the improvement in image quality is the result of partial compensation of the optical aberrations of the rodent eye by the contact lens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.