Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Aberrant SKP1 Expression: Diverse Mechanisms Impacting Genome and Chromosome Stability.Frontiers in cell and developmental biology · 2022
   Review
2. Postoperative Circulating Tumor DNA Can Predict High Risk Patients with Colorectal Cancer Based on Next-Generation Sequencing.Cancers · 2021
   Article
3. Enhancing the landscape of colorectal cancer using targeted deep sequencing.Scientific reports · 2021
   Article
4. Targeted next-generation sequencing of cancer genes in poorly differentiated thyroid cancer.Endocrine connections · 2018
   Article
5. Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer.Cancer research · 2017
   Article
6. Molecular Characterization of Somatic Alterations in Dukes' B and C Colorectal Cancers by Targeted Sequencing.Frontiers in pharmacology · 2017
   Article
7. Sirtuin 7 plays an oncogenic role in human osteosarcoma via downregulating CDC4 expression.American journal of cancer research · 2017
   Article
8. Molecular spectrum ofJournal of gastrointestinal oncology · 2016
   Article
9. FBXW7 negatively regulates ENO1 expression and function in colorectal cancer.Laboratory investigation; a journal of technical methods and pathology · 2015
   Article
10. Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions.Oncotarget · 2014
    Article
11. FBW7-mediated ubiquitination and degradation of KLF5.World journal of biological chemistry · 2014
    Review

Corrections and comments

• Comment on
  Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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