ReviewClinical & developmental immunology2013
Immunity to Polyomavirus BK Infection: Immune Monitoring to Regulate the Balance between Risk of BKV Nephropathy and Induction of Alloimmunity.
Review in Clinical & developmental immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Unveiling the mediating role of immune cells in the link between pathogen infections and Hashimoto's thyroiditis.The Journal of international medical research · 2026Article
- Adoptive T-cell therapy for virus-associated diseases.Clinical microbiology reviews · 2025Review
- The Accuracy of Blood Nucleic Acid Testing to Predict BK Polyomavirus Nephropathy Varies by Clinical Context.Transplantation direct · 2025Article
- Polyomavirus nephropathy: diagnosis, histologic features, and differentiation from acute rejection.Clinical transplantation and research · 2024Review
- Clinical and immunological characteristics for BK polyomavirus-associated nephropathy after kidney transplantation.Immunity, inflammation and disease · 2023Article
- Immunogenic Properties and Antigenic Similarity of Virus-like Particles Derived from Human Polyomaviruses.International journal of molecular sciences · 2023Article
- Lesson for the clinical nephrologist: immune monitoring of human JC-polyomavirus in kidney transplantation.Journal of nephrology · 2022Article
- The effect of BKV reactivation on cytokines behavior in kidney transplanted patients.BMC nephrology · 2022Article
- Proteomic analysis of urinary extracellular vesicles of kidney transplant recipients with BKV viruria and viremia: A pilot study.Frontiers in medicine · 2022Article
- Article
- The Role of HLA and KIR Immunogenetics in BK Virus Infection after Kidney Transplantation.Viruses · 2020Review
- Development of a Nucleic Acid Lateral Flow Immunoassay for the Detection of Human Polyomavirus BK.Diagnostics (Basel, Switzerland) · 2020Article
- BK Virus Nephropathy: Prevalence, Impact and Management Strategies.International journal of nephrology and renovascular disease · 2020Review
- The immunophenotyping of different stages of BK virus allograft nephropathy.Renal failure · 2019Article
- The Authors Reply.Journal of the American Society of Nephrology : JASN · 2018Article
- Polyoma virus nephropathy in kidney transplantation.World journal of transplantation · 2017Review
- BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies.Clinical microbiology reviews · 2017Review
- Pre-transplant immune factors may be associated with BK polyomavirus reactivation in kidney transplant recipients.PloS one · 2017Observational
- BK nephropathy in the native kidneys of patients with organ transplants: Clinical spectrum of BK infection.World journal of transplantation · 2016Review
- Symptomatic BK Virus Infection Is Associated With Kidney Function Decline and Poor Overall Survival in Allogeneic Hematopoietic Stem Cell Recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyomavirus BK-associated nephropathy (PyVAN) is the main infectious cause of allograft damage after kidney transplantation. A number of studies revealed an association between the presence of BKV-specific cellular immunity and BK viral clearance, with patients failing to recover specific T cells progressing to PyVAN. Evolution to allograft dysfunction can be prevented by restoration of BKV-specific immunity through a stepwise reduction of maintenance immunosuppressive drugs. Prospective monitoring of BK viral load and specific immunity, together with B-cell alloimmune surveillance, may allow a targeted modification/reduction of immunosuppression, with the aim of obtaining viral clearance while preventing graft injury due to deposition of de novo donor-specific HLA antibodies and late/chronic antibody-mediated allograft injury. Innovative, immune-based therapies may further contribute to BKV infection prevention and control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.