Evidence map›Paper›PMID 23999953›Full record

SynthesisPediatrics2013

Medication adherence and health care utilization in pediatric chronic illness: a systematic review.

Meghan E McGrady, Kevin A Hommel

Registry-linked trialOpen access · bronzeAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01802580 (Using an Internet Study to Improve Adherence for Psoriasis Patients), which is not on this map. Cited by 107 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 8 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01802580 early_phase1completednot on this map

Using an Internet Study to Improve Adherence for Psoriasis Patients

TypeinterventionalSponsorWake Forest UniversityRan2012 to 2016Enrolled40ConditionsPsoriasisArmsInternet Survey, fluocinonide 0.05% ointment
3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 8 syntheses or guidelines pooled it, 226 citations in OpenAlex.

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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Meghan E McGradyCenter for Adherence and Self-Management, Cincinnati Children's Hospital Medical, Center MLC 7039, 3333 Burnet Ave, Cincinnati, OH 45229-3026. meghan.mcgrady@cchmc.org.
Kevin A Hommel
Cincinnati Children's Hospital Medical Center · US

Funding

Enhancing treatment adherence and health outcomesT32HD068223 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Kevin Hommel, Meghan Eileen McGrady · 2012 to 2026
$3.6M
Telehealth Enhancement of Adherence to Medication in Pediatric IBD (TEAM Study)R01HD067174 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI HOMMEL, KEVIN · 2011 to 2015
$2.7M
NICHD NIH HHS R01 HD067174NICHD NIH HHS R01HD067174NICHD NIH HHS T32 HD068223NICHD NIH HHS T32HD068223
6 · The paper itself

Abstract

BACKGROUND AND

objectiveAdvanced understanding of modifiable predictors of health care use in pediatric chronic illness is critical to reducing health care costs. We examined the relationship between medication non-adherence and health care use in children and adolescents who have a chronic medical condition.

methodsA systematic review of articles by using PubMed, PsycINFO, and CINAHL was conducted. Additional studies were identified by searching reference sections of relevant manuscripts. Studies that tested the relationship between medication non-adherence and health care use (ie, hospitalizations, emergency department visits, outpatient visits) or cost in children and adolescents (mean age ≤18 years) who have a chronic medical condition were included. Extraction of articles was completed by using predefined data fields.

resultsTen studies met our inclusion criteria. Nine of the 10 studies reviewed (90%) demonstrated a relationship between medication non-adherence and increased health care use. The directionality of this relationship varied depending on the outcome variable of interest.

conclusionsMedication non-adherence is related to increased health care use in children and adolescents who have a chronic medical condition and should be addressed in clinical care. Future studies should include randomized controlled trials examining the impact of adherence promotion efforts on health care use and costs.

Indexed as

Medication AdherencePediatricsAdolescentChildChronic DiseaseDelivery of Health CareHumansRandomized Controlled Trials as Topicchronic diseasehealth care costshealth care quality, access, and evaluationmedication adherence

Identifiers

PMID23999953
PMCPMC3784296
OpenAlexW1970169019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.