Epilepsy: GRIN2A mutations identified as key genetic drivers of epilepsy-aphasia spectrum disorders.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.Epilepsy & behavior : E&B · 2025
   Article
2. Neurodevelopmental disorder due to a frameshift mutation in theTranslational pediatrics · 2025
   Article
3. Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.medRxiv : the preprint server for health sciences · 2025
   Article
4. Continuous Spike-Waves during Slow Sleep Today: An Update.Children (Basel, Switzerland) · 2024
   Review
5. Postsynaptic movement disorders: clinical phenotypes, genotypes, and disease mechanisms.Journal of inherited metabolic disease · 2018
   Review
6. Phenotypic analysis of 303 multiplex families with common epilepsies.Brain : a journal of neurology · 2017
   Article
7. GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function.Journal of human genetics · 2017
   Article
8. A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome.Cell reports · 2016
   Article
9. The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes.eLife · 2014
   Article

Corrections and comments

• Comment on
  GRIN2A mutations cause epilepsy-aphasia spectrum disorders.2013
• Comment on
  Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.2013
• Comment on
  GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as