ReviewHormones and behavior2013
The development of psychotic disorders in adolescence: a potential role for hormones.
Review in Hormones and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Stressful life events during adolescence and risk for externalizing and internalizing psychopathology: a meta-analysis.European child & adolescent psychiatry · 2017Pooled it
- Self-Reported Psychosis Spectrum Symptoms Among Sexual and Gender Diverse Emerging Adults Screened for a Suicide Prevention Trial.Archives of sexual behavior · 2026Article
- Early Pubertal Development Is a Risk Factor for Psychotic-Like Experiences in Boys and Girls.Biological psychiatry global open science · 2026Article
- Microecological modulators-new perspectives for treating sex hormone disorders.Frontiers in microbiology · 2026Review
- Executive functions and cognitive disengagement syndrome as predictors of suicidal behaviour: the mediating role of psychotic-like experiences.BMJ neurology open · 2026Article
- Article
- Use of Artificial Intelligence in Adolescents' Mental Health Care: Systematic Scoping Review of Current Applications and Future Directions.JMIR mental health · 2025Article
- Article
- Cognitive Dysfunction as a Risk Factor for Psychosis.Current topics in behavioral neurosciences · 2023Article
- The Critical Roles of Early Development, Stress, and Environment in the Course of Psychosis.Annual review of developmental psychology · 2022Article
- Peripheral biomarkers to predict the diagnosis of bipolar disorder from major depressive disorder in adolescents.European archives of psychiatry and clinical neuroscience · 2022Article
- Equity in Mental Health Services for Youth at Clinical High Risk for Psychosis: Considering Marginalized Identities and Stressors.Evidence-based practice in child and adolescent mental health · 2022Article
- Systematic discovery of signaling pathways linking immune activation to schizophrenia.iScience · 2021Article
- Adolescent Neurodevelopment and Vulnerability to Psychosis.Biological psychiatry · 2021Review
- Attenuated Psychotic Symptoms in Adolescents With Chronic Cannabis and MDMA Use.Frontiers in psychiatry · 2021Article
- Timing of menarche and abnormal hippocampal connectivity in youth at clinical-high risk for psychosis.Psychoneuroendocrinology · 2020Article
- Glucose Metabolism, Thyroid Function, and Prolactin Level in Adolescent Patients With First Episode of Schizophrenia and Affective Disorders.Frontiers in psychiatry · 2020Article
- The Brain Emotional Systems in Addictions: From Attachment to Dominance/Submission Systems.Frontiers in human neuroscience · 2020Article
- Disruptions in White Matter Maturation and Mediation of Cognitive Development in Youths on the Psychosis Spectrum.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2019Article
- Adult report of childhood imaginary companions and adversity relates to concurrent prodromal psychosis symptoms.Psychiatry research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
This article is part of a Special Issue "Puberty and Adolescence". The notion that adolescence is characterized by dramatic changes in behavior, and often by emotional upheaval, is widespread and longstanding in popular western culture. In recent decades, this notion has gained increasing support from empirical research showing that the peri- and post-pubertal developmental stages are associated with a significant rise in the rate of psychiatric symptoms and syndromes. As a result, interest in adolescent development has burgeoned among researchers focused on the origins of schizophrenia and other psychotic disorders. Two factors have fueled this trend: 1) increasing evidence from longitudinal research that adolescence is the modal period for the emergence of "prodromal" manifestations, or precursors of psychotic symptoms, and 2) the rapidly accumulating scientific findings on brain structural and functional changes occurring during adolescence and young adulthood. Further, gonadal and adrenal hormones are beginning to play a more prominent role in conceptualizations of adolescent brain development, as well as in the origins of psychiatric symptoms during this period (Walker and Bollini, 2002; Walker et al., 2008). In this paper, we begin by providing an overview of the nature and course of psychotic disorders during adolescence/young adulthood. We then turn to the role of hormones in modulating normal brain development, and the potential role they might play in the abnormal brain changes that characterize youth at clinical high-risk (CHR) for psychosis. The activational and organizational effects of hormones are explored, with a focus on how hormone-induced changes might be linked with neuropathological processes in the emergence of psychosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.