ArticleBioMed research international2013
Noninvasive monitoring of training induced muscle adaptation with 31P-MRS: fibre type shifts correlate with metabolic changes.
Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Physiological Resilience: What Is It and How Might It Be Trained?Scandinavian journal of medicine & science in sports · 2025Review
- Long-term detraining reverses the improvement of lifelong exercise on skeletal muscle ferroptosis and inflammation in aging rats: fiber-type dependence of the Keap1/Nrf2 pathway.Biogerontology · 2023Article
- Molecular imaging in masseter muscle observed by muscle function magnetic resonance imaging andClinical and experimental dental research · 2022Article
- Article
- Localized semi-LASER dynamic (31)P magnetic resonance spectroscopy of the soleus during and following exercise at 7 T.Magma (New York, N.Y.) · 2015Article
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7 authors.
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Abstract
purposeTo evaluate training induced metabolic changes noninvasively with (31)P magnetic resonance spectroscopy ((31)P-MRS) for measuring muscle fibre type adaptation.
methodsEleven volunteers underwent a 24-week training, consisting of speed-strength, endurance, and detraining (each 8 weeks). Prior to and following each training period, needle biopsies and (31)P-MRS of the resting gastrocnemius muscle were performed. Fibre type distribution was analyzed histologically and tested for correlation with the ratios of high energy phosphates ([PCr]/[P(i)], [PCr]/[βATP] and [PCr + P(i)]/[βATP]). The correlation between the changes of the (31)P-MRS parameters during training and the resulting changes in fibre composition were also analysed.
resultsWe observed an increased type-II-fibre proportion after speed-strength and detraining. After endurance training the percentage of fast-twitch fibres was reduced. The progression of the [PCr]/[P(i)]-ratio was similar to that of the fast-twitch fibres during the training. We found a correlation between the type-II-fibre proportion and [PCr]/[P(i)] (r = 0.70, P < 0.01) or [PCr]/[βATP] (r = 0.69, P < 0.01); the correlations between its changes (delta) and the fibre-shift were significant as well (delta[PCr]/[P(i)] r = 0.66, delta[PCr]/[βATP] r = 0.55, P < 0.01).
conclusionShifts in fibre type composition and high energy phosphate metabolite content covary in human gastrocnemius muscle. Therefore (31)P-MRS might be a feasible method for noninvasive monitoring of exercise-induced fibre type transformation.
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