ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2012
Chronic suppurative otitis media: optimizing initial antibiotic therapy in a tertiary care setup.
Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- Article
- Microbiology of Active Mucosal Chronic Otitis Media and Shifting Trends in Etiology in Idukki, Kerala: A Prospective Observational Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Bacteriological Profile and Antimicrobial Susceptibility Pattern in Chronic Suppurative Otitis Media: A 1-Year Cross-Sectional Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Comment to Empirical Therapy for Chronic Suppurative Otitis Media.Clinical medicine insights. Ear, nose and throat · 2018Article
- Anaerobic Bacteria in Clinical Specimens - Frequent, But a Neglected Lot: A Five Year Experience at a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2017Article
- Current concepts in the pathogenesis and treatment of chronic suppurative otitis media.Journal of medical microbiology · 2015Review
- Comparative bactericidal activity of four fluoroquinolones against Pseudomonas aeruginosa isolated from chronic suppurative otitis media.BMC ear, nose, and throat disorders · 2015Article
- Aetiological agents of ear discharge: a two year review in a teaching hospital in Ghana.Ghana medical journal · 2014Article
- Microbiology of chronic suppurative otitis media in a tertiary care setup of uttarakhand state, India.North American journal of medical sciences · 2013Article
- Observations on the current bacteriological profile of chronic suppurative otitis media in South eastern Nigeria.Annals of medical and health sciences researchArticle
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Authors and funding
6 authors.
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Abstract
A prospective study was done to determine the clinico-microbiological profile and the antibiogram of patients with chronic suppurative otitis media. Ninety-four patients presenting with tympanic perforation and ear discharge of more than 3 months were studied. Middle ear swabs obtained aseptically were processed for culture and the isolates identified by standard procedures. Antimicrobial susceptibility testing of the aerobic bacterial isolates was performed by disc diffusion method according to clinical laboratory standards institute guidelines. Patients in the age group of 21-30 years were more commonly affected (22.3%). Male:Female ratio was 2:1.4. Of the 94 patients, 64 (68.1%) had tubo-tympanic disease and rest 30 (31.9%) presented with attico-antral disease. Monomicrobial flora was seen in 55 (58.5%) samples, 28 (29.8%) yielded polymicrobial growth and 11 (11.7%) samples were sterile. A total of 115 microbial isolates (86 aerobic bacteria, 18 anaerobic bacteria and 11 fungi) were obtained. Pseudomonas aeruginosa (32.2%) was the most common isolate followed by Staphylococcus aureus (17.4%). Amongst anaerobes, gram positive cocci were more commonly isolated (38.9%). Aspergillus spp. (72.7%) were the most common fungus isolated. Most of the Pseudomonas aeruginosa isolates (25, 67.6%) were susceptible to all the antibiotics. Among the commonly used topical agents in the treatment of CSOM, tobramycin was the most effective (83.8%), followed by gentamicin (78.1%), ciprofloxacin (75.6%) and neomycin (3.5%). Periodic monitoring of the microbiological profile along with their sensitivity pattern is essential for formulating an effective antibiotic policy for CSOM.
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