ReviewEuropean respiratory review : an official journal of the European Respiratory Society2013
Sleep disorders in COPD: the forgotten dimension.
Review in European respiratory review : an official journal of the European Respiratory Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
93 citing papers in PubMed, 3 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- What is the most effective non-pharmacological treatment for poor sleep quality in Chronic obstructive pulmonary disease patients? a systematic review.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Extrapulmonary effects of lung volume reduction in severe emphysema: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Pooled it
- Tiotropium Respimat Soft Mist Inhaler versus HandiHaler to improve sleeping oxygen saturation and sleep quality in COPD.Sleep & breathing = Schlaf & Atmung · 2016Trial
- Effect of tiotropium on night-time awakening and daily rescue medication use in patients with COPD.Respiratory research · 2016Trial
- Self-reported sleep quality and acute exacerbations of chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2015Trial
- Pulmonary rehabilitation and sleep quality: a before and after controlled study of patients with chronic obstructive pulmonary disease.NPJ primary care respiratory medicine · 2014Trial
- A randomized trial to determine the impact of indacaterol/glycopyrronium on nighttime oxygenation and symptoms in patients with moderate-to-severe COPD: the DuoSleep study.International journal of chronic obstructive pulmonary diseaseTrial
- Nasal high flow, but not supplemental OInternational journal of chronic obstructive pulmonary diseaseTrial
- Risk of Obstructive Sleep Apnea in Patients with Emphysema Versus Bronchiectasis: A Propensity Score-Matched Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Sleep-Disordered Breathing in Primary Ciliary Dyskinesia.Pediatric pulmonology · 2026Review
- Sleep phenotypes and clinical outcomes in individuals with chronic obstructive pulmonary disease: A cohort study.Sleep & breathing = Schlaf & Atmung · 2026Article
- New approaches to uncover COPD pathobiology and develop therapies.JCI insight · 2026Review
- Beyond the apnea-hypopnea index in COPD-OSA overlap syndrome: a mechanism-informed framework for nocturnal oxygenation and ventilation.Frontiers in physiology · 2026Review
- Assessing Sleep and Mental Health Disorders in COPD Patients During Severe Exacerbations.The open respiratory medicine journal · 2026Article
- Dietary Antioxidant Intake and Sleep Quality: Combined Effects on Chronic Obstructive Pulmonary Disease in NHANES 2005-2008 and Mendelian Randomization Analysis.Food science & nutrition · 2025Article
- Article
- Depression and Anxiety as Comorbidities in Chronic Obstructive Pulmonary Disease: A Comprehensive Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Associated factors of fatigue in patients with COPD: results from the FAntasTIGUE study.ERJ open research · 2025Article
- Association between lung function and sleep disorder symptoms in a community-based multi-site case-finding study.Journal of sleep research · 2025Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep in chronic obstructive pulmonary disease (COPD) is commonly associated with oxygen desaturation, which may exceed the degree of desaturation during maximum exercise, both subjectively and objectively impairing sleep quality. The mechanisms of desaturation include hypoventilation and ventilation to perfusion mismatching. The consequences of this desaturation include cardiac arrhythmias, pulmonary hypertension and nocturnal death, especially during acute exacerbations. Coexistence of COPD and obstructive sleep apnoea (OSA), referred to as overlap syndrome, has been estimated to occur in 1% of the general adult population. Overlap patients have worse sleep-related hypoxaemia and hypercapnia than patients with COPD or OSA alone. OSA has a similar prevalence in COPD as in a general population of similar age, but oxygen desaturation during sleep is more pronounced when the two conditions coexist. Management of sleep-related problems in COPD should particularly focus on minimising sleep disturbance via measures to limit cough and dyspnoea; nocturnal oxygen therapy is not generally indicated for isolated nocturnal hypoxaemia. Treatment with continuous positive airway pressure alleviates hypoxaemia, reduces hospitalisation and pulmonary hypertension, and improves survival.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.