Observational studyPediatric nephrology (Berlin, Germany)2013
Birth parameters and parental height predict growth outcome in children with chronic kidney disease.
Observational study in Pediatric nephrology (Berlin, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Birth characteristics and growth outcome in children with nephropathic cystinosis compared with other chronic kidney disease entities prior to kidney replacement therapy.Pediatric nephrology (Berlin, Germany) · 2026Article
- Growth hormone treatment in the pre-transplant period is associated with superior outcome after pediatric kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2022Article
- Incidence of and risk factors for short stature in children with chronic kidney disease: results from the KNOW-Ped CKD.Pediatric nephrology (Berlin, Germany) · 2021Article
- Determinants of growth after kidney transplantation in prepubertal children.Pediatric nephrology (Berlin, Germany) · 2021Article
- Bone Disease in CKD in Children.Calcified tissue international · 2021Review
- Strategies for Optimizing Growth in Children With Chronic Kidney Disease.Frontiers in pediatrics · 2020Review
- Kidney transplantation fails to provide adequate growth in children with chronic kidney disease born small for gestational age.Pediatric nephrology (Berlin, Germany) · 2017Observational
- Patterns of growth after kidney transplantation among children with ESRD.Clinical journal of the American Society of Nephrology : CJASN · 2015Observational
- Anthropometric and biochemical profile of children and adolescents with chronic kidney disease in a predialysis pediatric interdisciplinary program.TheScientificWorldJournal · 2015Observational
- Growth in children with chronic kidney disease and associated risk factors for short stature.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe analyzed the impact of birth parameters and parental height on long-term growth outcome in children with chronic kidney disease (CKD) stage 3-5.
methodsLinear growth was prospectively investigated in 509 children, with a mean follow-up of 4.1 years. Growth outcome was categorized in (i) poor growth (PG): height standard deviation score (SDS) during follow-up < -2.0 and/or actual or previous growth hormone (GH) treatment, and (ii) good growth (GG): height SDS ≥ -2.0 and no need for GH. A multivariate binary logistic regression model was constructed for predictors of PG outcome.
resultsPG was observed in 55 % of patients. The rate of pre-term and small for gestational age birth was significantly higher in children with PG compared to GG (43.2 vs. 25.6 % and 36.8 vs. 18.9 %; p < 0.001). Children with PG had significantly lower average values for gestational age, birth weight, length, and head circumference, umbilical cord pH, Apgar scores, and parental height than children with GG. Birth length, umbilical cord pH, and parental height were significant independent predictors of PG outcome (sensitivity 72.8 %, specificity 69.3 %).
conclusionsBirth parameters and parental height are independent predictors of growth outcome in children with CKD.
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