ArticleApplied and environmental microbiology2013
Genome sequence analysis indicates that the model eukaryote Nematostella vectensis harbors bacterial consorts.
Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed.
- Hunting for Helminths: short- and long-read shotgun metagenomics for helminth detection in faecal samples.PLoS neglected tropical diseases · 2026Article
- Unique Transcriptional Responses by the Sea Anemone Nematostella vectensis to Individual Bacteria: Roles for Bacterial Species, Secreted Products and the Microbiome.Molecular ecology · 2026Article
- Article
- ContScout: sensitive detection and removal of contamination from annotated genomes.Nature communications · 2024Article
- Article
- A Large-Scale Study into Protist-Animal Interactions Based on Public Genomic Data Using DNA Barcodes.Animals : an open access journal from MDPI · 2023Article
- Comparative transmission of bacteria from Artemia salina and Brachionus plicatilis to the cnidarian Nematostella vectensis.FEMS microbiology ecology · 2022Article
- Contamination detection in genomic data: more is not enough.Genome biology · 2022Review
- CONSULT: accurate contamination removal using locality-sensitive hashing.NAR genomics and bioinformatics · 2021Article
- Transcriptome-based target-enrichment baits for stony corals (Cnidaria: Anthozoa: Scleractinia).Molecular ecology resources · 2020Article
- Prevalence and Implications of Contamination in Public Genomic Resources: A Case Study of 43 Reference Arthropod Assemblies.G3 (Bethesda, Md.) · 2020Article
- Comparative genomics reveals the distinct evolutionary trajectories of the robust and complex coral lineages.Genome biology · 2018Article
- Horizontally transferred genes in the ctenophorePeerJ · 2018Article
- Decontaminating eukaryotic genome assemblies with machine learning.BMC bioinformatics · 2017Article
- A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule.BMC biology · 2016Article
- Article
- Horizontally Transferred Genetic Elements in the Tsetse Fly Genome: An Alignment-Free Clustering Approach Using Batch Learning Self-Organising Map (BLSOM).BioMed research international · 2016Article
- Experimental Evolution as an Underutilized Tool for Studying Beneficial Animal-Microbe Interactions.Frontiers in microbiology · 2016Review
- The genome of Aiptasia, a sea anemone model for coral symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Article
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2 authors.
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Abstract
Analysis of the genome sequence of the starlet sea anemone, Nematostella vectensis, reveals many genes whose products are phylogenetically closer to proteins encoded by bacteria or bacteriophages than to any metazoan homologs. One explanation for such sequence affinities could be that these genes have been horizontally transferred from bacteria to the Nematostella lineage. We show, however, that bacterium-like and phage-like genes sequenced by the N. vectensis genome project tend to cluster on separate scaffolds, which typically do not include eukaryotic genes and differ from the latter in their GC contents. Moreover, most of the bacterium-like genes in N. vectensis either lack introns or the introns annotated in such genes are false predictions that, when translated, often restore the missing portions of their predicted protein products. In a freshwater cnidarian, Hydra, for which a proteobacterial endosymbiont is known, these gene features have been used to delineate the DNA of that endosymbiont sampled by the genome sequencing project. We predict that a large fraction of bacterium-like genes identified in the N. vectensis genome similarly are drawn from the contemporary bacterial consorts of the starlet sea anemone. These uncharacterized bacteria associated with N. vectensis are a proteobacterium and a representative of the phylum Bacteroidetes, each represented in the database by an apparently random sample of informational and operational genes. A substantial portion of a putative bacteriophage genome was also detected, which would be especially unlikely to have been transferred to a eukaryote.
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